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甘肃省少数民族地区儿童氟斑牙患病情况及危险因素

吕程程,  陈晓燕,  张婕,  张勇,  杨琳,  闫娟,  刘艳丽,  张本忠

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文章导航 > 中华疾病控制杂志  > 2023 >  27(9): 1025-1029
吕程程, 陈晓燕, 张婕, 张勇, 杨琳, 闫娟, 刘艳丽, 张本忠. 甘肃省少数民族地区儿童氟斑牙患病情况及危险因素[J]. 中华疾病控制杂志, 2023, 27(9): 1025-1029. doi: 10.16462/j.cnki.zhjbkz.2023.09.007
引用本文: 吕程程, 陈晓燕, 张婕, 张勇, 杨琳, 闫娟, 刘艳丽, 张本忠. 甘肃省少数民族地区儿童氟斑牙患病情况及危险因素[J]. 中华疾病控制杂志, 2023, 27(9): 1025-1029. doi: 10.16462/j.cnki.zhjbkz.2023.09.007
shu
LYU Chengcheng, CHEN Xiaoyan, ZHANG Jie, ZHANG Yong, YANG Lin, YAN Juan, LIU Yanli, ZHANG Benzhong. Prevalence and risk factors of dental fluorosis among children from minority areas of Gansu Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(9): 1025-1029. doi: 10.16462/j.cnki.zhjbkz.2023.09.007
Citation: LYU Chengcheng, CHEN Xiaoyan, ZHANG Jie, ZHANG Yong, YANG Lin, YAN Juan, LIU Yanli, ZHANG Benzhong. Prevalence and risk factors of dental fluorosis among children from minority areas of Gansu Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(9): 1025-1029. doi: 10.16462/j.cnki.zhjbkz.2023.09.007
shu

甘肃省少数民族地区儿童氟斑牙患病情况及危险因素

doi: 10.16462/j.cnki.zhjbkz.2023.09.007
  • 1.

    兰州大学公共卫生学院劳动卫生与环境卫生研究所，兰州 730030

  • 2.

    甘肃省疾病预防控制中心地方病防制科，兰州 730030

  • 3.

    西宁市卫生健康委员会疾病预防控制科，西宁 810003

基金项目: 

甘肃省中医药科研课题 GZKP-2020-27

详细信息
    通讯作者:

    张本忠，E-mail: zhangbzh@lzu.edu.cn

  • 中图分类号: R181

Prevalence and risk factors of dental fluorosis among children from minority areas of Gansu Province

  • 1.

    Institute of Occupational Hygiene and Environmental Hygiene, School of Public Health, Lanzhou University, Lanzhou 730030, China

  • 2.

    Department of Endemic Disease Control, Gansu Provincial Center for Disease Control and Prevention, Lanzhou 730030, China

  • 3.

    Department of Disease Control and Prevention, Xining Municipal Health Commission, Xining 810003, China

Funds: 

Research Project of Traditional Chinese Medicine in Gansu Province GZKP-2020-27

More Information

    摘要
  • 摘要:   目的  了解甘肃省少数民族地区儿童氟斑牙的患病情况，探讨氟斑牙发病的危险因素。  方法  于2019年6―11月采用分层整群随机抽样方法，对甘肃省8个少数民族县的1 344名在校学生进行资料收集、氟斑牙诊断和尿样中氟化物检测。  结果  甘肃省少数民族地区8~12岁儿童氟斑牙患病率为29.1%，尿氟浓度几何均值为1.02 mg/L。居住在阿克塞哈萨克族自治县(阿克塞县)(OR=2.625, 95% CI: 1.530~4.597, P=0.001)、肃南裕固族自治县(肃南县)(OR=2.421, 95% CI: 1.411~4.154, P=0.001)、天祝藏族自治县(天祝县)(OR=2.813, 95% CI: 1.599~4.946, P＜0.001)和夏河县(OR=1.719, 95%CI: 1.022~2.892, P=0.041)、具有饮茶习惯(OR=1.508, 95% CI: 1.072~2.120, P=0.018)、年龄较大(8~12岁)(OR=1.122, 95% CI: 1.021~1.233, P=0.017)、尿氟浓度较高(0.10~5.87 mg/L)(OR=1.549, 95% CI: 1.223~1.962, P＜0.001)是影响儿童氟斑牙患病率的危险因素。  结论  甘肃省少数民族地区儿童氟斑牙患病率较高，地区、饮茶习惯、年龄、尿氟等因素均会影响氟斑牙患病率，应针对性地开展饮茶型地氟病持续性防制工作。
    Abstract:   Objective  This study seeks to understand the prevalence of dental fluorosis in children residing in ethnic minority areas of Gansu Province and to explore the risk factors of dental fluorosis.  Methods  Between June and November 2019, 1 344 students from eight ethnic minority counties in Gansu Province were included using the stratified cluster random sampling method. These participants underwent data collection, dental fluorosis diagnosis and fluoride detection in urine samples.   Results   The prevalence of dental fluorosis among children aged 8-12 years in minority areas of Gansu Province was 29.1%, with a geometric mean urinary fluoride concentration of 1.02 mg/L. Living in the areas of Aksai (OR=2.625, 95% CI: 1.530-4.597, P=0.001), Sunan (OR=2.421, 95% CI: 1.411-4.154, P=0.001), Tianzhu (OR=2.813, 95% CI: 1.599-4.946, P < 0.001) and Xiahe (OR=1.719, 95% CI: 1.022-2.892, P=0.041) counties, having tea-drinking habits (OR=1.508, 95% CI: 1.072-2.120, P=0.018), older age (8-12 years old)(OR = 1.122, 95% CI: 1.021-1.233, P=0.017) and high urinary fluoride concentration (0.10-5.87 mg/L)(OR=1.549, 95% CI: 1.223-1.962, P < 0.001) were risk factors affecting the prevalence of dental fluorosis in children.  Conclusions  The prevalence of dental fluorosis among children is high in ethnic minority areas of Gansu Province. The factors such as region, tea-drinking habits, age, and urinary fluoride can affect the prevalence of dental fluorosis. Continuous prevention and treatment of tea-drinking type dental fluorosis should be carried out in a targeted manner.
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  • 表  1  不同特征儿童氟斑牙患病情况比较

    Table  1.   Comparison of the prevalence of dental fluorosis in children with different characteristics

    特征 Feature 人数(占比/%)
    Number ofpeople(proportion/%)    		 正常
    Normal    		 氟斑牙分级 Classification of dental fluorosis 氟斑牙检出人数(占比/%)
    Number of detectedfluorosis(proportion/%)    		 χ2值
    value    		 P值
    value
    极轻度
    Extremelymild    		 轻度
    Mild    		 中度
    Moderate    		 重度
    Heavy
    地区/县 Region/county 172.559 < 0.001
      阿克塞 Aksai 244(18.2) 129 57 50 7 1 115(47.1)
      康乐 Kangle 95(7.1) 82 8 3 2 0 13(13.7)
      玛曲 Maqu 216(16.1) 195 13 8 0 0 21(9.7)
      肃北 Subei 42(3.1) 37 4 1 0 0 5(11.9)
      肃南 Sunan 223(16.6) 117 59 24 23 0 106(47.5)
      天祝 Tianzhu 124(9.2) 67 26 22 7 2 57(46.0)
      夏河 Xiahe 180(13.4) 140 34 5 1 0 40(22.2)
      卓尼 Zhuoni 220(16.4) 186 19 14 0 1 34(15.5)
    民族 Nationality 117.933 < 0.001
      汉族 Han 187(13.9) 112 42 16 16 1 75(40.2)
      回族 Hui 112(8.3) 94 12 4 2 0 18(16.1)
      藏族 Tibetan 637(47.4) 517 74 40 5 1 120(18.9)
      裕固族 Yugur 134(10.0) 74 33 16 10 1 60(44.7)
      蒙古族 Mongolian 42(3.1) 37 4 1 0 0 5(11.9)
      哈萨克族 Kazak 232(17.3) 119 55 50 7 1 113(48.7)
    性别 Sex 2.119 0.145
      男 Male 663(49.3) 458 111 66 26 2 205(30.9)
      女 Female 681(50.7) 495 109 61 14 2 186(27.3)
    年龄组/岁 Age group/years 12.467 < 0.001
      8 262(19.5) 189 42 24 6 1 73(27.9)
      9 278(20.7) 213 42 17 6 0 65(23.4)
      10 331(24.6) 248 48 30 3 2 83(25.1)
      11 214(15.9) 146 35 22 11 0 68(31.8)
      12 259(19.3) 157 53 34 14 1 102(39.4)
    饮茶 Drinking tea 95.639 < 0.001
      无 No 682(50.7) 565 65 37 13 2 117(17.2)
      有 Yes 662(49.3) 388 155 90 27 2 274(41.4)
    合计 Total 1 344(100.0) 953 220 127 40 4 391(29.1)
    下载: 导出CSV

    表  2  不同氟斑牙分级、地区儿童尿氟浓度情况比较

    Table  2.   Comparison of urinary fluoride concentration among children in different dental fluorosis grades and regions

    特征 Feature 检测份数
    Number ofdetections    		 尿氟浓度/(mg·L-1)
    Urine fluoride concentration /(mg·L-1)    		 超标(> 1.4 mg·L-1)
    Exceeding standard(> 1.4 mg·L-1)
    G M 范围
    Scopey
    氟斑牙 Dental fluorosis
      否 No 953 0.91 0.90 0.10~5.87 否 No
      是 Yes 391 1.39 1.42 0.18~5.43 否 No
    氟斑牙分级 Classification of dental fluorosis
      极轻度 Extremely mild 220 1.33 1.30 0.18~5.43 否 No
      轻度 Mild 127 1.42 1.50 0.25~4.12 是 Yes
      中度 Moderate 40 1.63 1.51 0.22~5.43 是 Yes
      重度 Heavy 4 1.50 1.69 0.61~2.93 是 Yes
    地区(县) Region(county)
      阿克塞 Aksai 244 1.60 1.61 0.25~5.87 是 Yes
      康乐 Kangle 95 0.54 0.55 0.13~3.61 否 No
      玛曲 Maqu 216 0.90 0.90 0.46~2.09 否 No
      肃北 Subei 42 0.90 0.86 0.39~1.56 否 No
      肃南 Sunan 223 1.74 1.64 0.57~5.70 是 Yes
      天祝 Tianzhu 124 1.64 1.68 0.53~5.22 是 Yes
      夏河 Xiahe 180 0.63 0.63 0.20~2.81 否 No
      卓尼 Zhuoni 220 0.65 0.60 0.10~3.52 否 No
    合计 Total 1 344 1.02 1.05 0.10~5.87 否 No
    下载: 导出CSV

    表  3  儿童氟斑牙患病的多因素logistic回归分析

    Table  3.   Multivariate logistic regression analysis of dental fluorosis in children

    自变量 Factor β s Wald值
    value    		 OR值
    value(95% CI)    		 P值
    value
    地区(县)(ref: 卓尼)Region (county) (ref: Zhuoni)
      阿克塞 Aksai 0.975 0.281 12.086 2.652(1.530~4.597) 0.001
      肃南 Sunan 0.884 0.275 10.306 2.421(1.411~4.154) 0.001
      天祝 Tianzhu 1.034 0.288 12.890 2.813(1.599~4.946) < 0.001
      夏河 Xiahe 0.542 0.265 4.169 1.719(1.022~2.892) 0.041
    饮茶(ref: 否)Drink tea (ref: no) 0.411 0.174 5.580 1.508(1.072~2.120) 0.018
    年龄组/岁 Age group/years 0.115 0.048 5.679 1.122(1.021~1.233) 0.017
    尿氟浓度/(mg·L-1) Urine fluoride concentration/(mg·L-1) 0.438 0.121 13.170 1.549(1.223~1.962) < 0.001
    下载: 导出CSV
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  • 收稿日期:  2022-04-11
  • 修回日期:  2022-07-01
  • 网络出版日期:  2023-10-12
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