病毒宏基因组学在蜱媒病毒研究中的应用进展

孙世伟; 陆振华; 龙泳; 邵中军

doi:10.16462/j.cnki.zhjbkz.2024.03.018

病毒宏基因组学在蜱媒病毒研究中的应用进展

doi: 10.16462/j.cnki.zhjbkz.2024.03.018

孙世伟^{1, 2},
陆振华¹,
龙泳^1, ,,
邵中军^1, ,

1.
空军医科大学公共卫生学院特殊作业环境危害评价与控制教育部重点实验室流行病学教研室，西安 710032
2.
包头医学院公共卫生学院，包头 014000

基金项目:

国家自然科学基金 82273689

军队后勤科研计划重点项目 BWS20J020

军队医学科技青年培育计划拔尖项目 21QNPY087

详细信息

通讯作者:
邵中军, E-mail: 13759981783@163.com

龙泳, E-mail: longyong71@163.com

中图分类号: R373;R181
计量
- 文章访问数: 24
- HTML全文浏览量: 8
- PDF下载量: 3
- 被引次数: 0
出版历程
- 收稿日期: 2022-06-27
- 修回日期: 2022-09-23
- 网络出版日期: 2024-04-08
- 刊出日期: 2024-03-10

Application progress of virus metagenomics in study of tick-borne virus

SUN Shiwei^{1, 2},
LU Zhenhua¹,
LONG Yong^{1
, ,},
SHAO Zhongjun^{1
, ,}

1.
Department of Epidemiology, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, The Air Force Medical University, Xi′an 710032, China
2.
School of Public Health, Baotou Medical College, Baotou 014000, China

Funds:

National Natural Science Foundation of China 82273689

Major Projects of Military Logistics Scientific Research ProgramMajor Projects of Military Logistics Scientific Research Program BWS20J020

The Top-Notch Project of the Military Medical Science and Technology Youth Training Program 21QNPY087

More Information

Corresponding author: LONG Yong, E-mail: longyong71@163.com; SHAO Zhongjun, E-mail: 13759981783@163.com

摘要

摘要: 蜱是广泛分布于全球的专性吸血体外寄生虫，是世界上最主要的病媒生物之一，携带的病原体涵盖了细菌、病毒、螺旋体等。其中以蜱媒病毒为主要的虫媒病毒之一，给人类和动物的健康带来了极大的威胁。病毒宏基因组学是近年来基于宏基因组学兴起的病毒研究技术，它的出现为研究已知和未知病毒及其多样性提供了有力支持，给病毒研究带来了全新的技术手段和思路。本文综述了病毒宏基因组学在蜱媒病毒研究中的进展，以期为蜱媒病毒研究提供参考依据。
- 蜱 /
- 蜱媒病毒 /
- 宏基因组学 /
- 高通量测序
Abstract: Ticks are specific blood-sucking ectoparasites which are widely distributed all over the world. They are one of the most important vector organism in the world, carrying pathogens including bacteria, viruses, spirochetes etc. Among them, tick-borne virus is the major arbovirus, which brings great burden to human and animal health. Virus metagenomics have been a virus research technology based on metagenomics in recent years. Its emergence provides strong support for the study of known and unknown viruses and their diversity, and brings new technical means and ideas to virus research. This paper reviews the research progress of viral metagenomics in tick-borne virus research to provide useful reference for tick-borne virus research.
- Ticks /
- Tick-borne virus /
- Metagenomics /
- High-throughput sequencing

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表 1 我国主要蜱媒病毒、媒介蜱种及其地理分布

Table 1. Major TBV, tick vector species and their geographical distribution in China

蜱媒病毒 Tick-borne virus	主要媒介蜱种 Major vector tick species	主要分布地区(省) Main distribution areas (provinces)
森林脑炎病毒 Tick-borne encephalitis virus	全沟硬蜱、卵形硬蜱、嗜群血蜱、森林革蜱、微小扇头蜱 I.persulcatus, I.ovatus, Ha.concinna, D.silvarum, R.microplus	黑龙江、吉林、新疆、内蒙古等地 Heilongjiang, Jilin, Xinjiang, Inner Mongolia, et al
发热伴血小板减少综合征布尼亚病毒 Severe fever with thrombocytopenia syndrome Virus	长角血蜱、微小扇头蜱 Ha.longicornis, R.microplus	河南、湖北、安徽、山东、辽宁等地 Henan, Hubei, Anhui, Shandong, Liaoning, et al
克里米亚-刚果出血热病毒 Crimean-Congo hemorrhagic fever virus	亚洲璃眼蜱、小亚璃眼蜱、囊形扇头蜱 Hy.asiaticum, Hy.anatolicum, R.bursa	新疆、云南等地 Xinjiang, Yunnan, et al
阿龙山病毒 Alongshan virus	全沟硬蜱 I.persulcatus	内蒙古、黑龙江、吉林等地 Inner Mongolia, Heilongjiang, Jilin, et al
松岭病毒 Songling virus	全沟硬蜱、长角血蜱 I.persulcatus, Ha.longicornis	黑龙江、吉林、内蒙古等地 Heilongjiang, Jilin, Inner Mongolia, et al

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