Carriage prevalence and drug resistance profile of MRSA and MSSA strains isolated from newborns

WANG Ying-ying; ZHOU Xin; WU Chuan-an; ZHENG Hui-jie; ZHENG Hao-qu; YAO Zhen-jiang

doi:10.16462/j.cnki.zhjbkz.2019.10.027

Volume 23 Issue 10

Oct. 2019

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WANG Ying-ying, ZHOU Xin, WU Chuan-an, ZHENG Hui-jie, ZHENG Hao-qu, YAO Zhen-jiang. Carriage prevalence and drug resistance profile of MRSA and MSSA strains isolated from newborns[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(10): 1297-1300. doi: 10.16462/j.cnki.zhjbkz.2019.10.027

Citation:

WANG Ying-ying, ZHOU Xin, WU Chuan-an, ZHENG Hui-jie, ZHENG Hao-qu, YAO Zhen-jiang. Carriage prevalence and drug resistance profile of MRSA and MSSA strains isolated from newborns[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(10): 1297-1300. doi: 10.16462/j.cnki.zhjbkz.2019.10.027

Citation:

WANG Ying-ying, ZHOU Xin, WU Chuan-an, ZHENG Hui-jie, ZHENG Hao-qu, YAO Zhen-jiang. Carriage prevalence and drug resistance profile of MRSA and MSSA strains isolated from newborns[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(10): 1297-1300. doi: 10.16462/j.cnki.zhjbkz.2019.10.027

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Carriage prevalence and drug resistance profile of MRSA and MSSA strains isolated from newborns

doi: 10.16462/j.cnki.zhjbkz.2019.10.027

1.
Faculty of Epidemiology and Health Statistics, School of public health, Guangdong pharmaceutical university, Guangzhou 510310, China
2.
Department of Information, Shenzhen Longhua New District Maternal and Child Health Center, Shenzhen 518109, China

Funds:

Science and Technology Plan Project of Guangdong Provence 2014A020213013

Innovation and Strong School Project of Guangdong Pharmaceutical University 2016

More Information

Corresponding author: YAO Zhen-jiang, E-mail: zhjyao2001@yahoo.com
Received Date: 2019-04-01
Rev Recd Date: 2019-07-10
Publish Date: 2019-10-10

Abstract

Abstract

Objective To determine the carriage prevalence and antibiotics resistance profile of methicillin-resistant staphylococcus aureus(MRSA) and methicillin-sensitive staphylococcus aureus(MSSA) strains isolated from newborns. Methods A cross-sectional study was conducted in two hospitals in Shenzhen from August to November 2015. Cotton swab samples were collected from 1834 newborns. Staphylococcus aureus was identified by general laboratory tests, and antimicrobial-susceptibility profiles was tested. Results In total, 3.27% (60/1 834) Staphylococcus aureus (SA) strains were isolated, including 0.82% (15/1 834) MRSA and 2.45% (45/1 834) MSSA. Most MRSA and MSSA strains were resistant to penicillin and erythromycin but less than 10% strains resistant to linezolid. Drugs resistance rates of MRSA to erythromycin, moxifloxacin and clindamycin were all higher than that of MSSA (all P < 0.05). The multidrug-resistant risk of MRSA (80.00%) was 12.36 times higher than that of MSSA (24.44%). Conclusions Multidrug-resistant SA especially MRSA strains isolated from newborns had the higher prevalence, the drugs resistance rate of MRSA strains was more serious than that of MSSA.
- Newborns,
- MRSA,
- MSSA,
- Carriage prevalence,
- Antibiotics resistance profile

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References(11)

References

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