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CN 34-1304/RISSN 1674-3679

Volume 25 Issue 1
Jan.  2021
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ZHI Hong, HU Jia-shu, WANG Ai-lian, GUAN Jie-qiong, SONG Wen-jing, WANG Li-na. A case-control study on risk factors for atrial fibrillation among people over 50 years old in a community in Nanjing[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(1): 90-94. doi: 10.16462/j.cnki.zhjbkz.2021.01.017
Citation: ZHI Hong, HU Jia-shu, WANG Ai-lian, GUAN Jie-qiong, SONG Wen-jing, WANG Li-na. A case-control study on risk factors for atrial fibrillation among people over 50 years old in a community in Nanjing[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(1): 90-94. doi: 10.16462/j.cnki.zhjbkz.2021.01.017

A case-control study on risk factors for atrial fibrillation among people over 50 years old in a community in Nanjing

doi: 10.16462/j.cnki.zhjbkz.2021.01.017
Funds:

General Project of Jiangsu Commission of Health H2019079

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  • Corresponding author: WANG Li-na, E-mail:lnwang@seu.edu.cn
  • Received Date: 2020-10-12
  • Rev Recd Date: 2020-12-18
  • Publish Date: 2021-01-10
  •   Objective  To explore the risk factors of atrial fibrillation (AF) in people aged 50 years and above in Nanjing, Jiangsu Province.  Methods  An epidemiological survey was conducted among the elderly in a community healthcare center in Qixia District from March 1, 2019 to April 30, 2019. The case group was defined as patients with AF diagnosed by 12-lead electrocardiogram (ECG), and the controls were a non-AF population matched by age and sex, with a matching ratio of 1:4. Univariate and multivariate conditional Logistic regression analysis model were used to analyse possible influencing factors.  Results  A total of 3 444 cases were investigated. The ratio of male to female is 1:2, and the detection rate of AF was 1.19%. The univariate Logistic regression analysis indicated that serum uric acid (OR=1.01, 95% CI: 1.00-1.01), hematocrit (HCT, OR=1.11, 95% CI: 1.01-1.23) and red blood cell distribution width (RDW, OR=1.50, 95% CI: 1.05-2.14) might be risk factors for AF. The multivariate Logistic regression analysis model results showed that each increase of 1% in HCT and RDW was associated with a 13% (OR=1.13, 95% CI: 1.01-1.27) and 61% (OR=1.61, 95% CI: 1.00-2.59) increased risk of AF respectively.  Conclusions  HCT and RDW may be independent risk factors for atrial fibrillation in the elderly in Nanjing community. In addition, the results of this study need to be further verified due to the limited sample size.
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