Association between cardiovascular and cerebrovascular diseases and cognition among Chinese aged 50 years and older

LIU Qing; HUANG Zhe-zhou; GUO Yan-fei; RUAN Ye; SUN Shuang-yuan; SHI Yan; WU Fan

doi:10.16462/j.cnki.zhjbkz.2021.03.009

Volume 25 Issue 3

Mar. 2021

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2021 > 25(3): 295-299

LIU Qing, HUANG Zhe-zhou, GUO Yan-fei, RUAN Ye, SUN Shuang-yuan, SHI Yan, WU Fan. Association between cardiovascular and cerebrovascular diseases and cognition among Chinese aged 50 years and older[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(3): 295-299. doi: 10.16462/j.cnki.zhjbkz.2021.03.009

Citation:

LIU Qing, HUANG Zhe-zhou, GUO Yan-fei, RUAN Ye, SUN Shuang-yuan, SHI Yan, WU Fan. Association between cardiovascular and cerebrovascular diseases and cognition among Chinese aged 50 years and older[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(3): 295-299. doi: 10.16462/j.cnki.zhjbkz.2021.03.009

Citation:

LIU Qing, HUANG Zhe-zhou, GUO Yan-fei, RUAN Ye, SUN Shuang-yuan, SHI Yan, WU Fan. Association between cardiovascular and cerebrovascular diseases and cognition among Chinese aged 50 years and older[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(3): 295-299. doi: 10.16462/j.cnki.zhjbkz.2021.03.009

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Association between cardiovascular and cerebrovascular diseases and cognition among Chinese aged 50 years and older

doi: 10.16462/j.cnki.zhjbkz.2021.03.009

1.
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
2.
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China

Funds:

The US National Institute on Aging R01-AG034479

Shanghai Municipal Health Commission 20204Y0196

Shanghai Municipal Health Commission 2020YJZX0113

Shanghai Municipal Health Commission 201840118

Shanghai Municipal Health Commission 201640148

Shanghai Municipal Health Commission 20174Y0147

Program for Outstanding Medical Academic Leader, Shanghai, China 2019LJ24

More Information

Corresponding author: WU Fan, E-mail: wufan@shmu.edu.cn
Received Date: 2020-09-17
Rev Recd Date: 2020-12-18
Publish Date: 2021-03-10

Abstract

Abstract

Objective To investigate the association between cardiovascular and cerebrovascular diseases and cognition among Chinese aged 50 and over. Methods Data was collected from the World Health Organization study on global ageing and adult health wave in China. A comprehensive battery of cognitive tests was conducted to assess subjects' cognitive functions, including immediate and delayed verbal recall, digit span and verbal fluency. Cardiovascular and cerebrovascular diseases included hypertension, angina and stroke. General linear model was used to examine the association of cardiovascular and cerebrovascular diseases with cognition. Results A total of 12 645 adults aged 50 and over who did cognitive tests and without obvious cognitive impairment were selected as participants. Compared with people without cardiovascular and cerebrovascular diseases, people who only had angina had lower scores in immediate and delayed verbal recall and composite cognition (all P < 0.05). Participants who had both hypertension and angina had lower scores in immediate and delayed verbal recall, digit span, verbal fluency and composite cognition (all P < 0.05). Participants who had both hypertension and stroke had lower scores in immediate and delayed verbal recall, digit span and composite cognition (all P < 0.05). Participants who had both angina and stroke had lower scores in digit span and composite cognition (all P < 0.05). Participants who had all of hypertension, angina and stroke had lower score in digit span (P=0.019). The number of cardiovascular and cerebrovascular diseases was negatively associated with immediate and delayed verbal recall, digit span, verbal fluency and composite cognition (all P < 0.05). Conclusions Comorbid cardiovascular and cerebrovascular diseases were associated with worse cognitive function.
- Elderly,
- Cognition,
- Cardiovascular and cerebrovascular diseases

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References(18)

References

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