Characteristics of population susceptible to hepatitis B infection in Guangzhou, 2008 and 2018

LU Ying; HUANG Yong; WANG Hui; YANG Qiong-ying; ZHANG Zhou-bin; ZHANG Chun-huan

doi:10.16462/j.cnki.zhjbkz.2021.03.017

Volume 25 Issue 3

Mar. 2021

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LU Ying, HUANG Yong, WANG Hui, YANG Qiong-ying, ZHANG Zhou-bin, ZHANG Chun-huan. Characteristics of population susceptible to hepatitis B infection in Guangzhou, 2008 and 2018[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(3): 341-345. doi: 10.16462/j.cnki.zhjbkz.2021.03.017

Citation:

LU Ying, HUANG Yong, WANG Hui, YANG Qiong-ying, ZHANG Zhou-bin, ZHANG Chun-huan. Characteristics of population susceptible to hepatitis B infection in Guangzhou, 2008 and 2018[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(3): 341-345. doi: 10.16462/j.cnki.zhjbkz.2021.03.017

Citation:

LU Ying, HUANG Yong, WANG Hui, YANG Qiong-ying, ZHANG Zhou-bin, ZHANG Chun-huan. Characteristics of population susceptible to hepatitis B infection in Guangzhou, 2008 and 2018[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(3): 341-345. doi: 10.16462/j.cnki.zhjbkz.2021.03.017

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Characteristics of population susceptible to hepatitis B infection in Guangzhou, 2008 and 2018

doi: 10.16462/j.cnki.zhjbkz.2021.03.017

1.
Department of Infectious Disease, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
2.
Department of Immunization Planning, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
3.
Department of Health and Education, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China
4.
Director's Office, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China

Funds:

Guangzhou Medical Key Discipline Construction Project 2017-2019-07

Guangzhou Science and Technology Project 201804010191

More Information

Corresponding author: ZHANG Chun-huan, E-mail: 27797328@qq.com
Received Date: 2020-12-01
Rev Recd Date: 2021-01-26
Publish Date: 2021-03-10

Abstract

Abstract

Objective To compare the epidemiological characteristics of hepatitis B virus susceptible population aged 1-59 in Guangzhou in 2008 and 2018, and to evaluate the effect of immunization strategy. Methods A two-stage cluster sampling method was used to conduct the seroepidemiological survey of hepatitis B among permanent residents aged 1-59 in Guangzhou in 2008 and 2018. Results In the two surveys the prevalence rates of HBV susceptibility were 17.34% (95% CI: 16.29%-18.39%) and 19.77% (95% CI: 18.54%-21.01%) among the population aged 1 to 59 years, and were 23.93% and 36.22% among the population aged 7 to 16 years. The prevalence rates of single anti-HBc positivity were 6.63% (95% CI: 5.94%-7.33%) and 2.76% (95% CI: 1.62%-3.91%) in two surveys among the population aged 1 to 59 years, the difference was statistically significant. The positive rate of single anti-HBc decreased by 81.73% in the population with history of hepatitis B vaccine immunization. Conclusions Efforts should be made to strengthen the implementation of catch-up vaccination, booster vaccination and revaccination in susceptible population, including the single anti-HBc positive population.
- Hepatitis,
- Seroepidemiology,
- Disease susceptibility,
- Hepatitis B core antibody,
- Hepatitis B vaccine

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References(10)

References

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