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CN 34-1304/RISSN 1674-3679

Volume 25 Issue 10
Nov.  2021
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Article Contents
SHI Wan-ying, CHEN Chen, CAO Ya-qiang, ZHANG Yi, CUI Qian, ZHAO Feng, WANG Jiao-nan, FANG Jian-long, TANG Song, LI Tian-tian, SHI Xiao-ming. Impact of persistent high ambient fine particulate matters exposure on cardiometabolic risk factors among middle-aged and elderly people[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(10): 1120-1125, 1168. doi: 10.16462/j.cnki.zhjbkz.2021.10.002
Citation: SHI Wan-ying, CHEN Chen, CAO Ya-qiang, ZHANG Yi, CUI Qian, ZHAO Feng, WANG Jiao-nan, FANG Jian-long, TANG Song, LI Tian-tian, SHI Xiao-ming. Impact of persistent high ambient fine particulate matters exposure on cardiometabolic risk factors among middle-aged and elderly people[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2021, 25(10): 1120-1125, 1168. doi: 10.16462/j.cnki.zhjbkz.2021.10.002

Impact of persistent high ambient fine particulate matters exposure on cardiometabolic risk factors among middle-aged and elderly people

doi: 10.16462/j.cnki.zhjbkz.2021.10.002
Funds:

National Natural Science Foundation of China 81573247

National Key Research and Development Program of China 2016YFC0206500

National research program for key issues in air pollution control DQGG0401

More Information
  • Corresponding author: SHI Xiao-ming, E-mail: shixm@chinacdc.cn
  • Received Date: 2021-06-08
  • Rev Recd Date: 2021-08-02
  • Available Online: 2021-11-17
  • Publish Date: 2021-10-10
  •   Objective  To explore the effects of persistent high exposure of fine particulate matters (PM2.5) on cardiometabolic risk factors among middle-aged and older people in Beijing-Tianjin-Hebei and surrounding regions.  Methods  A cross-sectional survey was conducted from April 9th, 2017 to March 31st, 2019 in 6 Provinces in Beijing-Tianjin-Hebei and the surrounding areas. A total of 2 415 middle-aged and elderly people aged 40 to 89 years were recruited as the research participants. Questionnaire survey was conducted to obtain the basic information, socioeconomic and lifestyle of the participants. Physical examination was carried out to obtain waist circumference, levels of fasting blood glucose, blood pressure, triglycerides and high-density lipoprotein cholesterol. According to the consensus statement from the International Diabetes Federation in 2005, the co-prevalence of cardiometabolic risk factors was defined. Daily mean PM2.5 concentrations ≥75 μg/m3, ≥90th percentile of daily mean PM2.5 concentrations in each County during the survey year and various durations (≥2 d or ≥3 d) were used to define PM2.5 high exposure scenarios and persistent states. Logistic regression model was used to analyze the effects of persistent high exposure of PM2.5 on co-prevalence of cardiometabolic risk factors.  Results  Persistent high exposure of PM2.5 was significantly associated with the co-prevalence of cardiometabolic factors, especially when extreme pollution scenario was defined by P90 and lasted for more than 2 days and 3 days, OR value (95% CI) of elevated risk of co-prevalence of cardiometabolic factors were 1.58 (1.00-2.50) and 2.57 (1.27-5.22), respectively. The increase of blood glucose and triglyceride level were more sensitive metabolic risk factors. Moreover, subgroup analysis showed that persistent high PM2.5 exposure had a more substantial impact on cardiometabolic risks in males and people under 65 years.  Conclusions  Persistent high exposure of PM2.5 in Beijing-Tianjin-Hebei and surrounding regions in China can significantly increase cardiometabolic risks in middle-aged and older people.
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