Status and influencing factors of latent tuberculosis infection among middle school students in Taizhou from 2019 to 2021

WANG Wen-jin; LIU Qiao; MIAO Chang-dong; CHEN Jing-juan; WANG Zhan; ZHU Li-mei; LU Wei

doi:10.16462/j.cnki.zhjbkz.2022.11.005

Volume 26 Issue 11

Nov. 2022

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WANG Wen-jin, LIU Qiao, MIAO Chang-dong, CHEN Jing-juan, WANG Zhan, ZHU Li-mei, LU Wei. Status and influencing factors of latent tuberculosis infection among middle school students in Taizhou from 2019 to 2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(11): 1264-1270. doi: 10.16462/j.cnki.zhjbkz.2022.11.005

Citation:

WANG Wen-jin, LIU Qiao, MIAO Chang-dong, CHEN Jing-juan, WANG Zhan, ZHU Li-mei, LU Wei. Status and influencing factors of latent tuberculosis infection among middle school students in Taizhou from 2019 to 2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(11): 1264-1270. doi: 10.16462/j.cnki.zhjbkz.2022.11.005

Citation:

WANG Wen-jin, LIU Qiao, MIAO Chang-dong, CHEN Jing-juan, WANG Zhan, ZHU Li-mei, LU Wei. Status and influencing factors of latent tuberculosis infection among middle school students in Taizhou from 2019 to 2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(11): 1264-1270. doi: 10.16462/j.cnki.zhjbkz.2022.11.005

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Status and influencing factors of latent tuberculosis infection among middle school students in Taizhou from 2019 to 2021

doi: 10.16462/j.cnki.zhjbkz.2022.11.005

1.
Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China
2.
Institute of Chronic Infectious Diseases, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
3.
Department of Chronic Infectious Disease Control, Taizhou Center for Disease Control and Prevention, Taizhou 225300, China

Funds:

National Nature Science Foundation of China 82003516

Medical Scientific Research General Project of Jiangsu Health Commission ZD2021052

Medical Scientific Research General Project of Jiangsu Health Commission ZDA2020022

Medical Scientific Research General Project of Jiangsu Health Commission M2020020

More Information

Corresponding author: LU Wei, E-mail: jsjkmck@163.com
Received Date: 2022-03-06
Rev Recd Date: 2022-05-20

Available Online: 2022-12-21

Publish Date: 2022-11-10

Abstract

Abstract

Objective To describe the prevalence of latent tuberculosis infection and analyze the influencing factors of latent tuberculosis infection among middle school freshmen from 2019 to 2021 in Taizhou City, Jiangsu Province, and to provide a reference for tuberculosis prevention and control in school. Methods The physical examination data and tuberculin skin test (TST) results of freshmen were collected, and the risk factors related to latent tuberculosis infection were collected by questionnaire. Logistic regression analysis model was used to analyze the data. Results A total of 23 910 participants aged 13-18 years old were included. The overall latent tuberculosis infection rate of tuberculosis among middle school students in Taizhou was 5.675%. Multivariate analysis results showed that senior high school students (aOR=1.569, 95% CI: 1.083-2.273, P=0.017), 18.5 kg/m²≤BMI≤23.9 kg/m²(aOR=1.415, 95% CI: 1.196-1.674, P < 0.001), BMI>23.9 kg/m² (aOR=1.643, 95% CI: 1.358-1.988, P < 0.001), previous tuberculosis (aOR=5.026, 95% CI: 2.264-11.155, P < 0.001) were the risk factors of latent tuberculosis infection. Conclusions Effective ways to prevent latent tuberculosis infection in middle school students include increasing outdoor exercise time, reducing stress appropriately, improving body immunity, and balancing diet nutrition to maintain proper BMI.
- Pulmonary tuberculosis,
- Middle school freshmen,
- Latent infection,
- Tuberculin skin test

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References(18)

References

[1]	WHO. Global tuberculosis report 2021[EB/OL]. (2021-10-14)[2022-02-10]. https://www.who.int/publications/i/item/9789240037021.
[2]	WHO. The end TB strategy[EB/OL]. (2015-08-16)[2022-02-10]. https://www.who.int/teams/global-tuberculosis-programme/the-end-tb-strategy.
[3]	虞浩, 刘巧, 丁晓艳, 等. 江苏省结核病疫情周报在学校结核病预警及处置中的应用[J]. 江苏预防医学, 2021, 32(5): 522-525. DOI: 10.13668/j.issn.1006-9070.2021.05.003. Yu H, Liu Q, Ding XY, et al. Application of weekly report of tuberculosis epidemic in Jiangsu Province in early warning and treatment of tuberculosis in schools[J]. Jiangsu Prev Med, 2021, 32(5): 522-525. DOI: 10.13668/j.issn.1006-9070.2021.05.003.
[4]	Vynnycky E, Fine PE. The natural history of tuberculosis: the implications of age-dependent risks of disease and the role of reinfection[J]. Epidemiol Infect, 1997, 119(2): 183-201. DOI: 10.1017/s0950268897007917.
[5]	Andrews JR, Noubary F, Walensky RP, et al. Risk of progression to active tuberculosis following reinfection with Mycobacterium tuberculosis[J]. Clin Infect Dis, 2012, 54(6): 784-791. DOI: 10.1093/cid/cir951.
[6]	中华人民共和国国家卫生和计划生育委员会. 学校结核病防控工作规范(2017版)[EB/OL]. (2017-06-26)[2022-02-10]. http://www.nhc.gov.cn/jkj/s7914/201707/4d2f57086b65450c8f674bf07323b9ad.shtml. National Health and Family Planning Commission of The Pepple's Republic of China. Norms for tuberculosis prevention and control in schools (2017 edition)[EB/OL]. (2017-06-26)[2022-02-10]. http://www.nhc.gov.cn/jkj/s7914/201707/4d2f57086b65450c8f674bf07323b9ad.shtml.
[7]	中华人民共和国国家卫生健康委员会. 中国学校结核病防控指南(2020版)[EB/OL]. (2020-10-16)[2022-02-10]. http://www.nhc.gov.cn/jkj/s7923/202012/5f40b53827ae41c5ab7827507d584cab.shtml. National Health Commission of The People's Republic of China. Guidelines for tuberculosis prevention and control in Chinese schools (2020 edition)[EB/OL]. (2020-10-16)[2022-02-10]. http://www.nhc.gov.cn/jkj/s7923/202012/5f40b53827ae41c5ab7827507d584cab.shtml.
[8]	中华人民共和国国家卫生和计划生育委员会. 肺结核诊断标准(WS 288-2017)[J]. 新发传染病电子杂志, 2018, 3(1): 59-61. DOI: 10.19871/j.cnki.xfcrbzz.2018.01.017. National Health and Family Planning Commission of The Pepple's Republic of China. Diagnostic for pulmonary tuberculosis standard(WS 288-2017)[J]. Chin J Antituberc, 2018, 3(1): 59-61. DOI: 10.19871/j.cnki.xfcrbzz.2018.01.017.
[9]	中华人民共和国国家卫生和计划生育委员会. 结核病分类WS 196-2017[EB/OL]. (2017-11-09)[2022-02-10]. http://www.nhc.gov.cn/wjw/s9491/201712/0d3c52de984b4bc4add047f19ccd51b9.shtml. National Health Commission of The People's Republic of China. Tuberculosis classification WS 196-2017[EB/OL]. (2017-11-09)[2022-02-10]. http://www.nhc.gov.cn/wjw/s9491/201712/0d3c52de984b4bc4add047f19ccd51b9.shtml.
[10]	吴蕴华, 苏华林, 唐利红, 等. 分类筛查在上海市闵行区入学新生肺结核筛查中的应用[J]. 中国初级卫生保健, 2020, 34(11): 63-65. DOI: 10.3969/j.issn.1001-568X.2020.11.0017. Wu YH, Su HL, Tang LH, et al. The application of classification screening in tuberculosis screening for new students enrolled in Shaohang district, Shanghai[J]. Chin Prim Heal Care, 2020, 34(11): 63-65. DOI: 10.3969/j.issn.1001-568X.2020.11.0017.
[11]	尹立, 张雯. 太原市某区4所高中2016年-2018年入学新生结核病筛查结果分析[J]. 护理研究, 2020, 34(14): 2589-2592. DOI: 10.12102/j.issn.1009-6493.2020.14.033. Yin L, Zhang W. Analysis of tuberculosis screening results among freshmen in 4 senior high schools in a district in Taiyuan from 2016 to 2018[J]. Chinese Nursing Research, 2020, 34(14): 2589-2592. DOI: 10.12102/j.issn.1009-6493.2020.14.033.
[12]	马聪兴, 张秀芝, 王鹛, 等. 2019年北京市朝阳区高中及以下阶段新生入学肺结核筛查结果分析[J]. 现代预防医学, 2020, 47(21): 3908-3910. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202021019.htm Ma CX, Zhang XZ, Wang M, et al. Tuberculosis screening results among new students of high schools and below in Chaoyang district of Beijing, 2019[J]. Mod Prev Med, 2020, 47(21): 3908-3910. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202021019.htm
[13]	孔雯, 刘巧, 卢鹏, 等. 江苏省部分地区结核潜伏性感染影响因素研究[J]. 江苏预防医学, 2018, 29(3): 244-246. DOI: 10.13668/j.issn.1006-9070.2018.03.003. Kong W, Liu Q, Lu P, et al. Analysis of factors affecting latent tuberculosis infection in partial areas of Jiangsu Province[J]. Jiangsu J Prev Med, 2018, 29(3): 244-246. DOI: 10.13668/j.issn.1006-9070.2018.03.003.
[14]	Mancuso JD, Diffenderfer JM, Ghassemieh BJ, et al. The prevalence of latent tuberculosis infection in the United States[J]. Am J Respir Crit Care Med, 2016, 194(4): 501-509. DOI: 10.1164/rccm.201508-1683OC.
[15]	Gao L, Lu W, Bai LQ, et al. Latent tuberculosis infection in rural China: baseline results of a population-based, multicentre, prospective cohort study[J]. Lancet Infect Dis, 2015, 15(3): 310-319. DOI: 10.1016/S1473-3099(14)71085-0.
[16]	Friedman EE, Khan A, Duffus WA. Screening for latent tuberculosis infection among HIV-infected Medicaid enrollees[J]. Public Health Rep, 2018, 133(4): 413-422. DOI: 10.1177/0033354918776639.
[17]	杨本付, 庄斌. 结核病环境危险因素研究进展[J]. 预防医学论坛, 2008, 14(9): 815-817. DOI: 10.3969/j.issn.1672-9153.2008.09.022. Yang BF, Zhuang B. Research progress in environmental risk factors of tuberculosis[J]. Prev Med Tribune, 2008, 14(9): 815-817. DOI: 10.3969/j.issn.1672-9153.2008.09.022.
[18]	LoBue PA, Mermin JH. Latent tuberculosis infection: the final frontier of tuberculosis elimination in the USA[J]. Lancet Infect Dis, 2017, 17(10): e327-e333. DOI: 10.1016/S1473-3099(17)30248-7.