Advanced Search

CN 34-1304/RISSN 1674-3679

Volume 27 Issue 4
Apr.  2023
Turn off MathJax
Article Contents
ZHENG Yang, WU Han, LIU Xiaoxia, WANG Yingquan, LIU Danni, SU Qiuyun, YANG Qundi, SHI Yan, FU Chen. Mediating effect analysis of smoking on the association between socioeconomic status and hypertriglyceridemia[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(4): 437-442. doi: 10.16462/j.cnki.zhjbkz.2023.04.011
Citation: ZHENG Yang, WU Han, LIU Xiaoxia, WANG Yingquan, LIU Danni, SU Qiuyun, YANG Qundi, SHI Yan, FU Chen. Mediating effect analysis of smoking on the association between socioeconomic status and hypertriglyceridemia[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2023, 27(4): 437-442. doi: 10.16462/j.cnki.zhjbkz.2023.04.011

Mediating effect analysis of smoking on the association between socioeconomic status and hypertriglyceridemia

doi: 10.16462/j.cnki.zhjbkz.2023.04.011
ZHENG Yang and WU Han contributed equally to this article
Funds:

Shanghai Municipal Health Commission Youth Projects 20204Y0195

New Star in Medical Circle of Shanghai-Public Health Leader Project 202199

More Information
  • Corresponding author: FU Chen, E-mail: fuchen@scdc.sh.cn
  • Received Date: 2022-07-07
  • Rev Recd Date: 2022-09-30
  • Available Online: 2023-04-28
  • Publish Date: 2023-04-10
  •   Objective  To examine the mediating effects of smoking on the relationship between socioeconomic status (SES) and hypertriglyceridemia, and to further provide the scientific basis for preventing and treating hypertriglyceridemia.  Methods  A total of 5 557 adult residents from the Shanghai Chronic Disease and Risk Factors Surveillance in 2017 were included in the study. The participants were investigated with questionnaires, body measurements, and laboratory testing. The chi-square and Wilcoxon rank sum tests were used to explore the distributional differences in qualitative and quantitative data, respectively. Mediation effect analysis was adopted to study the effects of SES on hypertriglyceridemia mediated by smoking.  Results  SES was associated with smoking (OR=0.86, 95% CI: 0.81-0.91, P < 0.001), and there was a positive association between smoking and hypertriglyceridemia (OR=1.29, 95% CI: 1.04-1.59, P=0.019); SES did not have a direct effect on hypertriglyceridemia, but smoking was found to have a mediating effect on the association between SES and hypertriglyceridemia (Zmediation=-2.086, P=0.037).  Conclusions  The association between SES and hypertriglyceridemia was significantly completely mediated by smoking. Targeted tobacco control measures and campaigns should be carried out for better hypertriglyceridemia prevention.
  • loading
  • [1]
    国家卫生和计划生育委员会疾病预防控制局. 中国居民营养与慢性病状况报告(2015年)[M]. 北京: 人民卫生出版社, 2015: 1-116.

    National Health and Family Planning Commission of the People's Republic of China. The Report on the Status of Nutrition and Chronic Diseases of Chinese residents (2015)[M]. Beijing: People's Medical Publishing House, 2015: 1-116.
    [2]
    中国疾病预防控制中心. 中国慢性病及危险因素监测报告(2018年)[M]. 北京: 人民卫生出版社, 2021: 1-166.

    Chinese Center for Disease Control and Prevention. The report on chronic disease risk factor surveillance in China 2018[M]. Beijing: People's Medical Publishing House, 2021: 1-166.
    [3]
    Miller M, Stone NJ, Ballantyne C, et al. Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association[J]. Circulation, 2011, 123(20): 2292-2333. DOI: 10.1161/CIR.0b013e3182160726.
    [4]
    王薇, 刘静, 孙佳艺, 等. 甘油三酯水平与糖尿病发病危险的队列研究[J]. 中华内科杂志, 2012, 51(7): 516-519. DOI: 10.3760/cma.j.issn.0578-1426.2012.07.006.

    Wang W, Liu J, Sun JY, et al. The association between the changes in triglyceride levels and the risk of incident type 2 diabetes mellitus: a 15 years followed-up results from the Chinese Multi-provincial Cohort Study[J]. Chin J Intern Med, 2012, 51(7): 516-519. DOI: 10.3760/cma.j.issn.0578-1426.2012.07.006.
    [5]
    程冷眉, 朱丽萍, 颜玮, 等. 江西省成年居民糖调节受损和糖尿病患病状况及影响因素分析[J]. 中华疾病控制杂志, 2018, 22(5): 494-498. DOI: 10.16462/j.cnki.zhjbkz.2018.05.015.

    Cheng LM, Zhu LP, Yan W, et al. Analysis on the prevalence and influencing factors of impaired glucose regulation and diabetes among adult residents in Jiangxi Province[J]. Chin J Dis Control Prev, 2018, 22(5): 494-498. DOI: 10.16462/j.cnki.zhjbkz.2018.05.015.
    [6]
    Craig WY, Palomaki GE, Haddow JE. Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data[J]. BMJ, 1989, 298(6676): 784-788. DOI: 10.1136/bmj.298.6676.784.
    [7]
    中华人民共和国国家卫生健康委员会. 中国吸烟危害健康报告2020[M]. 北京: 人民卫生出版社, 2021: 1-168.

    National Health Commission of the People's Republic of China. The report on health hazards of smoking in China (2020)[M]. Beijing: People's Medical Publishing House, 2021: 1-168.
    [8]
    Galobardes B, Shaw M, Lawlor DA, et al. Indicators of socioeconomic position (part 2)[J]. J Epidemiol Community Health, 2006, 60(2): 95-101. DOI: 10.1136/jech.2004.028092.
    [9]
    Espírito Santo LR, Faria TO, Silva CSO, et al. Socioeconomic status and education level are associated with dyslipidemia in adults not taking lipid-lowering medication: a population-based study[J]. Int Health, 2019, 14(4): 346-353. DOI: 10.1093/inthealth/ihz089.
    [10]
    Yu ZJ, Nissinen A, Vartiainen E, et al. Socio-economic status and serum lipids: a cross-sectional study in a Chinese urban population[J]. J Clin Epidemiol, 2002, 55(2): 143-149. DOI: 10.1016/s0895-4356(01)00451-6.
    [11]
    周俊梅, 罗新萍, 王书, 等. 河南省农村地区居民血脂异常患病率及其危险因素调查[J]. 中华预防医学杂志, 2016, 50(9): 799-805. DOI: 10.3760/cma.j.issn.0253-9624.2016.09.010.

    Zhou JM, Luo XP, Wang S, et al. Prevalence and risk factors of dyslipidemia in a rural population of Henan Province, China[J]. Chin J Prev Med, 2016, 50(9): 799-805. DOI: 10.3760/cma.j.issn.0253-9624.2016.09.010.
    [12]
    Shohaimi S, Boekholdt MS, Luben R, et al. Distribution of lipid parameters according to different socio-economic indicators- the EPIC-Norfolk prospective population study[J]. BMC Public Health, 2014, 14: 782. DOI: 10.1186/1471-2458-14-782.
    [13]
    严薇荣, 饶克勤, 王增珍. 中国居民吸烟与社会经济状况关系研究[J]. 中国公共卫生, 2004, 20(8): 928-929. DOI: 10.3321/j.issn:1001-0580.2004.08.014.

    Yan WR, Rao KQ, Wang ZZ. Smoking and socioeconomic status in China[J]. China Public Health, 2004, 20(8): 928-929. DOI: 10.3321/j.issn:1001-0580.2004.08.014.
    [14]
    Garrett BE, Martell BN, Caraballo RS, et al. Socioeconomic differences in cigarette smoking among sociodemographic groups[J]. Prev Chronic Dis, 2019, 16: E74. DOI: 10.5888/pcd16.180553.
    [15]
    Hiscock R, Bauld L, Amos A, et al. Socioeconomic status and smoking: a review[J]. Ann N Y Acad Sci, 2012, 1248: 107-123. DOI: 10.1111/j.1749-6632.2011.06202.x.
    [16]
    陆晔, 刘晓侠, 朱珍妮, 等. 上海市中老年人群优质蛋白质摄入与肌肉衰减症风险的关系研究[J]. 营养学报, 2020, 42(5): 429-434. DOI: 10.13325/j.cnki.acta.nutr.sin.2020.05.003.

    Lu Y, Liu XX, Zhu ZN, et al. Association between daily intake of high-quality proteins and sarcopenia in aging adults in Shanghai[J]. Acta Nutr Sin, 2020, 42(5): 429-434. DOI: 10.13325/j.cnki.acta.nutr.sin.2020.05.003.
    [17]
    中华医学会, 中华医学会杂志社, 中华医学会全科医学分会, 等. 血脂异常基层诊疗指南(实践版·2019)[J]. 中华全科医师杂志, 2019, 18(5): 417-421. DOI: 10.3760/cma.j.issn.1671-7368.2019.05.004.

    Chinese Medical Association, Journal of Chinese Medical Association, General Medicine Branch of Chinese Medical Association, et al. Guideline for primary care of dyslipidemias: practice version(2019)[J]. Chin J Gen Pract, 2019, 18(5): 417-421. DOI: 10.3760/cma.j.issn.1671-7368.2019.05.004.
    [18]
    Kumar N, Shekhar C, Kumar P, et al. Kuppuswamy's socioeconomic status scale-updating for 2007[J]. Indian J Pediatr, 2007, 74(12): 1131-1132.
    [19]
    李春玲. 当代中国社会的声望分层: 职业声望与社会经济地位指数测量[J]. 社会学研究, 2005, 20(2): 74-102, 244. DOI: 10.19934/j.cnki.shxyj.2005.02.004.

    Li CL. Prestige Stratification in the Contemporary China: occupational prestige measures and socio-economic index[J]. Sociol Res, 2005, 20(2): 74-102, 244. DOI: 10.19934/j.cnki.shxyj.2005.02.004.
    [20]
    Armstrong T, Bull F. Development of the World Health Organization global physical activity questionnaire (GPAQ)[J]. J Public Health, 2006, 14(2): 66-70. DOI: 10.1007/s10389-006-0024-x.
    [21]
    Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations[J]. J Pers Soc Psychol, 1986, 51(6): 1173-1182. DOI: 10.1037//0022-3514.51.6.1173.
    [22]
    MacKinnon DP, Krull JL, Lockwood CM. Equivalence of the mediation, confounding and suppression effect[J]. Prev Sci, 2000, 1(4): 173-181. DOI:10.1023/A: 1026595011371.
    [23]
    Shrout PE, Bolger N. Mediation in experimental and nonexperimental studies: new procedures and recommendations[J]. Psychol Methods, 2002, 7(4): 422-445.
    [24]
    Iacobucci D. Mediation analysis and categorical variables: the final frontier[J]. J Consumer Psychol, 2012, 22(4): 582-594. DOI: 10.1016/j.jcps.2012.03.006.
    [25]
    Harrill I, Jansen C, Barthrop J. Serum cholesterol and triglycerides and hyperlipoproteinemia in elderly women[J]. J Gerontol, 1978, 33(3): 347-353. DOI: 10.1093/geronj/33.3.347.
    [26]
    Sun GZ, Li Z, Guo L, et al. High prevalence of dyslipidemia and associated risk factors among rural Chinese adults[J]. Lipids Health Dis, 2014, 13(1): 189. DOI: 10.1186/1476-511X-13-189.
    [27]
    Brischetto CS, Connor WE, Connor SL, et al. Plasma lipid and lipoprotein profiles of cigarette smokers from randomly selected families: enhancement of hyperlipidemia and depression of high-density lipoprotein[J]. Am J Cardiol, 1983, 52(7): 675-680. DOI: 10.1016/0002-9149(83)90396-x.
    [28]
    姜博, 马爱娟, 谢晨, 等. 北京市18~65岁居民戒烟意愿、吸烟危害认知及其对吸烟情况的影响[J]. 中华流行病学杂志, 2020, 41(7): 1058-1062. DOI: 10.3760/cma.j.cn112338-20190812-00590.

    Jiang B, Ma AJ, Xie C, et al. Study on intention of smoking concession, awareness of smoking hazards and impact on smoking status in residents aged 18-65 years in Beijing[J]. Chin J Epidemiol, 2020, 41(7): 1058-1062. DOI: 10.3760/cma.j.cn112338-20190812-00590.
    [29]
    陈德, 蒋月英, 尉晓霞, 等. 2016年上海市居民烟草暴露和烟草危害的认知情况[J]. 上海预防医学, 2018, 30(8): 689-693. DOI: 10.19428/j.cnki.sjpm.2018.18828.

    Chen D, Jiang YY, Wei XX, et al. Awareness of tobacco exposure and tobacco hazards among residents of Shanghai in 2016[J]. Shanghai J Prev Med, 2018, 30(8): 689-693. DOI: 10.19428/j.cnki.sjpm.2018.18828.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(2)

    Article Metrics

    Article views (367) PDF downloads(35) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return