Association between early-onset family history and stroke prevalence in high-risk populations of cardiovascular disease

CHENG Ting-ting; SU Jian; QIN Yu; CUI Lan; DING Shuai; MIU Wei-gang; ZHOU Jin-yi; WU Ming

doi:10.16462/j.cnki.zhjbkz.2020.10.004

Volume 24 Issue 10

Nov. 2020

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CHENG Ting-ting, SU Jian, QIN Yu, CUI Lan, DING Shuai, MIU Wei-gang, ZHOU Jin-yi, WU Ming. Association between early-onset family history and stroke prevalence in high-risk populations of cardiovascular disease[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(10): 1129-1133. doi: 10.16462/j.cnki.zhjbkz.2020.10.004

Citation:

CHENG Ting-ting, SU Jian, QIN Yu, CUI Lan, DING Shuai, MIU Wei-gang, ZHOU Jin-yi, WU Ming. Association between early-onset family history and stroke prevalence in high-risk populations of cardiovascular disease[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(10): 1129-1133. doi: 10.16462/j.cnki.zhjbkz.2020.10.004

Citation:

CHENG Ting-ting, SU Jian, QIN Yu, CUI Lan, DING Shuai, MIU Wei-gang, ZHOU Jin-yi, WU Ming. Association between early-onset family history and stroke prevalence in high-risk populations of cardiovascular disease[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(10): 1129-1133. doi: 10.16462/j.cnki.zhjbkz.2020.10.004

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Association between early-onset family history and stroke prevalence in high-risk populations of cardiovascular disease

doi: 10.16462/j.cnki.zhjbkz.2020.10.004

Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210000, China

Funds:

NNational Major Public Health Service Project Cai She〔2014〕No.37

More Information

Corresponding author: WU Ming,E-mail:jswuming@vip.sina.com
Received Date: 2020-05-19
Rev Recd Date: 2020-08-16
Publish Date: 2020-10-10

Abstract

Abstract

Objective To investigate how the early-onset family history of stroke influences the stroke in high-risk populations of cardiovascular disease. Methods Based on the China Patient-centered Evaluative Assessment of Cardiac Events Million Persons Project (China PEACE-MPP) from 2015 to 2019, a total of 22 552 persons at high-risk for cardiovascular disease (CVD) were selected from eight project areas in Jiangsu. Logistic regression analysis model was used to research the impact of early-onset family history on stroke prevalence, and further analyses of the interaction between early-onset family history and hypertension or diabetes were carried on. Results Compared with people without early-onset family history, people with early-onset family history of stroke had a higher risk of stroke, with an OR value of 2.04 (95% CI:1.70-2.44). For the risk of ischemic stroke, people whose only male relatives, only female relatives and bisexual relatives suffering from stroke had a higher risk of stroke than those without early onset family history, with OR values of 2.18 (95% CI:1.68-2.84), 1.76 (95% CI:1.31-2.37) and 3.12 (95% CI:1.80-5.42), respectively. For the risk of hemorrhagic stroke, only female relatives type was not significant. No interaction between early-onset family history or hypertension and diabetes was found. Conclusions People at high risk of CVD with the early-onset family history have a higher risk of stroke. Lifestyle intervention and disease management should be carried out opportunely.
- Cardiovascular disease high-risk population,
- Early-onset family history,
- Stroke

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References(24)

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