A cross-sectional study of the association between handgrip strength and hypertension among adults in Lu′an City, Anhui Province, China

ZHOU Zhihao; LIU Mengfei; YE Shu; ZHOU Yumo; JIANG Cao; CHANG Hongwei; CAO Hongjuan; LIU Yang; SUN Zisuo; LI Meiling; ZHANG Zhuang; YANG Wanshui

doi:10.16462/j.cnki.zhjbkz.2025.02.006

Volume 29 Issue 2

Feb. 2025

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2025 > 29(2): 158-163

ZHOU Zhihao, LIU Mengfei, YE Shu, ZHOU Yumo, JIANG Cao, CHANG Hongwei, CAO Hongjuan, LIU Yang, SUN Zisuo, LI Meiling, ZHANG Zhuang, YANG Wanshui. A cross-sectional study of the association between handgrip strength and hypertension among adults in Lu′an City, Anhui Province, China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(2): 158-163. doi: 10.16462/j.cnki.zhjbkz.2025.02.006

Citation:

ZHOU Zhihao, LIU Mengfei, YE Shu, ZHOU Yumo, JIANG Cao, CHANG Hongwei, CAO Hongjuan, LIU Yang, SUN Zisuo, LI Meiling, ZHANG Zhuang, YANG Wanshui. A cross-sectional study of the association between handgrip strength and hypertension among adults in Lu′an City, Anhui Province, China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(2): 158-163. doi: 10.16462/j.cnki.zhjbkz.2025.02.006

Citation:

ZHOU Zhihao, LIU Mengfei, YE Shu, ZHOU Yumo, JIANG Cao, CHANG Hongwei, CAO Hongjuan, LIU Yang, SUN Zisuo, LI Meiling, ZHANG Zhuang, YANG Wanshui. A cross-sectional study of the association between handgrip strength and hypertension among adults in Lu′an City, Anhui Province, China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(2): 158-163. doi: 10.16462/j.cnki.zhjbkz.2025.02.006

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A cross-sectional study of the association between handgrip strength and hypertension among adults in Lu′an City, Anhui Province, China

doi: 10.16462/j.cnki.zhjbkz.2025.02.006

1.
Department of Nutrition, School of Public Health, Anhui Medical University, Hefei 230032, China
2.
Department of Endemic Diseases and STD/AIDS Prevention and Control, Huoshan County Center for Disease Control and Prevention, Lu′an 237200, China
3.
Department of Chronic Non-communicable Diseases Prevention and Control, Lu′an Municipal Center for Disease Control and Prevention, Lu′an 237000, China

Funds:

The National Natural Science Foundation of China 82373673

The National Key Research and Development Program of China 2023YFA1800800

Research Funds of Center for Big Data and Population Health of IHM JKS2022018

Grants from Anhui Medical University 2021xkjT007

Postgraduate Innovation Research and Practice Program of Anhui Medical University YJS20230104

Postgraduate Innovation Research and Practice Program of Anhui Medical University YJS20230150

More Information

Corresponding author: YANG Wanshui, E-mail: wanshuiyang@gmail.com
Received Date: 2024-04-15
Rev Recd Date: 2024-12-29

Available Online: 2025-03-08

Publish Date: 2025-02-10

Abstract

Abstract

Objective This study aimed to investigate the association between handgrip strength and hypertension, providing scientific evidence for the prevention, screening, and intervention of hypertension. Methods This study was based on a population-based cross-sectional study conducted in the Lu′an, Anhui Province, from July 2020 to July 2021. The handgrip strength was measured using a calibrated CAMRY handgrip strength dynamometer. Multivariable logistic regression was used to assess the association between handgrip strength and hypertension. Subgroup analyses were conducted according to factors such as age, gender, and BMI, and their interactions were analyzed using the Wald test. During the sensitivity analysis, participants with a family history of hypertension were excluded. Results Of the 2 694 participants, 1 309 (48.6%) were diagnosed with hypertension. After adjusting for age, gender, BMI, and other covariates, participants in the highest quartile of handgrip strength had a 39% lower risk of hypertension compared to those in the lowest quartile (OR=0.61, 95% CI: 0.43-0.86, P_trend < 0.001). Conclusions Greater handgrip strength is linked to a lower prevalence of hypertension, indicating that individuals should prioritize improving muscle strength in their daily routines to promote health and reduce the risk of developing hypertension.
- Handgrip strength,
- Hypertension,
- Cross-sectional study

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References(17)

References

[1]	Luo DL, Cheng YJ, Zhang HF, et al. Association between high blood pressure and long term cardiovascular events in young adults: systematic review and Meta-analysis[J]. BMJ, 2020, 370: m3222. DOI: 10.1136/bmj.m3222.
[2]	GBD Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the global burden of disease study 2019[J]. Lancet, 2020, 396(10258): 1223-1249. DOI: 10.1016/S0140-6736(20)30752-2.
[3]	Wolfe RR. The underappreciated role of muscle in health and disease[J]. Am J Clin Nutr, 2006, 84(3): 475-482. DOI: 10.1093/ajcn/84.3.475.
[4]	Wang DXM, Yao J, Zirek Y, et al. Muscle mass, strength, and physical performance predicting activities of daily living: a Meta-analysis[J]. J Cachexia Sarcopenia Muscle, 2020, 11(1): 3-25. DOI: 10.3310/LLBX6901.
[5]	Taekema DG, Gussekloo J, Maier AB, et al. Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old[J]. Age Ageing, 2010, 39(3): 331-337. DOI: 10.1093/ageing/afq022.
[6]	Zhang XX, Huang LL, Peng X, et al. Association of handgrip strength with hypertension among middle-aged and elderly people in Southern China: a cross-sectional study[J]. Clin Exp Hypertens, 2020, 42(2): 190-196. DOI: 10.1080/10641963.2019.1601206.
[7]	Ji C, Zheng LQ, Zhang R, et al. Handgrip strength is positively related to blood pressure and hypertension risk: results from the National Health and nutrition examination survey[J]. Lipids Health Dis, 2018, 17(1): 86. DOI: 10.1186/s12944-018-0734-4.
[8]	雷文慧, 何诗琪, 王豪, 等. 中老年男性吸烟状况与心血管疾病发生风险的关联性[J]. 中华疾病控制杂志, 2019, 23(7): 774-779. DOI: 10.16462/j.cnki.zhjbkz.2019.07.007. Lei WH, He SQ, Wang H, et al. Association of smoking status and cardiovascular disease in the middle-aged and older male populations[J]. Chin J Dis Control Prev, 2019, 23(7): 774-779. DOI: 10.16462/j.cnki.zhjbkz.2019.07.007.
[9]	李亚茹, 王婧, 赵丽云, 等. 中国成年人饮酒习惯及影响因素[J]. 中华流行病学杂志, 2018, 39(7): 898-903. DOI: 10.3760/cma.j.issn.0254-6450.2018.07.007. Li YR, Wang J, Zhao LY, et al. The drinking status and associated factors in adults in China[J]. Chin J Epidemiol, 2018, 39(7): 898-903. DOI: 10.3760/cma.j.issn.0254-6450.2018.07.007.
[10]	朱玉, 李昊伟, 周志豪, 等. 低碳水化合物饮食与高血糖关联的横断面研究[J]. 中华疾病控制杂志, 2023, 27(5): 540-545, 604. DOI: 10.16462/j.cnki.zhjbkz.2023.05.008. Zhu Y, Li HW, Zhou ZH, et al. Cross-sectional study on the relationship between low carbohydrate diet and hyperglycemia[J]. Chin J Dis Control Prev, 2023, 27(5): 540-545, 604. DOI: 10.16462/j.cnki.zhjbkz.2023.05.008.
[11]	Ainsworth BE, Haskell WL, Leon AS, et al. Compendium of physical activities: classification of energy costs of human physical activities[J]. Med Sci Sports Exerc, 1993, 25(1): 71-80. DOI: 10.1249/00005768-199301000-00011.
[12]	Polo-López A, Calatayud J, Núñez-Cortés R, et al. Dose-response association between handgrip strength and hypertension: a longitudinal study of 76 503 european older adults[J]. Curr Probl Cardiol, 2023, 48(9): 101813. DOI: 10.1016/j.cpcardiol.2023.101813.
[13]	Fecchio RY, Brito LC, Peçanha T, et al. Potential mechanisms behind the blood pressure-lowering effect of dynamic resistance training[J]. Curr Hypertens Rep, 2021, 23(6): 35. DOI: 10.1007/s11906-021-01154-5.
[14]	Millar PJ, McGowan CL, Cornelissen VA, et al. Evidence for the role of isometric exercise training in reducing blood pressure: potential mechanisms and future directions[J]. Sports Med, 2014, 44(3): 345-356. DOI: 10.1007/s40279-013-0118-x.
[15]	Zavaroni I, Bonini L, Gasparini P, et al. Hyperinsulinemia in a normal population as a predictor of non-insulin-dependent diabetes mellitus, hypertension, and coronary heart disease: the Barilla factory revisited[J]. Metabolism, 1999, 48(8): 989-994. DOI: 10.1016/s0026-0495(99)90195-6.
[16]	Galipeau DM, Yao LF, McNeill JH. Relationship among hyperinsulinemia, insulin resistance, and hypertension is dependent on sex[J]. Am J Physiol Heart Circ Physiol, 2002, 283(2): H562-H567. DOI: 10.1152/ajpheart.00238.2002.
[17]	Modan M, Halkin H. Hyperinsulinemia or increased sympathetic drive as links for obesity and hypertension[J]. Diabetes Care, 1991, 14(6): 470-487. DOI: 10.2337/diacare.14.6.470.