Trend of lower respiratory infections burden and age-period-cohort analysis of Chinese residents from 1990 to 2021

WANG Yan; DING Xiao; HAN Ruiyang; FENG Wenjia; CHEN Junli; MA Anning

doi:10.16462/j.cnki.zhjbkz.2025.04.002

Volume 29 Issue 4

Apr. 2025

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WANG Yan, DING Xiao, HAN Ruiyang, FENG Wenjia, CHEN Junli, MA Anning. Trend of lower respiratory infections burden and age-period-cohort analysis of Chinese residents from 1990 to 2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(4): 378-386. doi: 10.16462/j.cnki.zhjbkz.2025.04.002

Citation:

WANG Yan, DING Xiao, HAN Ruiyang, FENG Wenjia, CHEN Junli, MA Anning. Trend of lower respiratory infections burden and age-period-cohort analysis of Chinese residents from 1990 to 2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(4): 378-386. doi: 10.16462/j.cnki.zhjbkz.2025.04.002

Citation:

WANG Yan, DING Xiao, HAN Ruiyang, FENG Wenjia, CHEN Junli, MA Anning. Trend of lower respiratory infections burden and age-period-cohort analysis of Chinese residents from 1990 to 2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(4): 378-386. doi: 10.16462/j.cnki.zhjbkz.2025.04.002

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Trend of lower respiratory infections burden and age-period-cohort analysis of Chinese residents from 1990 to 2021

doi: 10.16462/j.cnki.zhjbkz.2025.04.002

1.
School of Public Health, Shandong Second Medical University, Weifang 261053, China
2.
Institute of Public Health Crisis Management, Shandong Second Medical University, Weifang 261053, China

Funds:

Ministry of Education Humanities and Social Sciences Research Planning Project 22YJAZH081

Major Project of Shandong Provincial Key Research and Development Program (Soft Science Project) 2020RZB14001

Weifang Municipal Health Commission Project 37070000007500120220034

More Information

Corresponding author: MA Anning, E-mail: yxyman@126.com
Received Date: 2024-08-13
Rev Recd Date: 2025-01-05
Publish Date: 2025-04-10

Abstract

Abstract

Objective To analyze the trends in the burden of lower respiratory infections (LRIs) among Chinese residents from 1990 to 2021, and to provide a reference for developing and adjusting prevention strategies as well as evaluating the effectiveness of control measures. Methods Using data from the global burden of disease study 2021 (GBD 2021) on LRIs among Chinese residents from 1990 to 2021, a descriptive analysis was conducted based on incidence, mortality, and disability-adjusted life year (DALY). Joinpoint regression models were used to analyze trends in disease burden, while age-period-cohort models were employed to assess the effects of age, period, and cohort on mortality rates. Results From 1990 to 2021, age-standardized incidence rates (ASIR), age-standardized mortality rates (ASMR), and age-standardized DALY rates (ASDR) for LRIs in China showed a declining trend, decreasing by 47.93%, 76.87%, and 88.89%, with average annual percentage changes (AAPC) of-2.12% (95% CI:-2.20%--2.04%),-4.77% (95% CI:-5.14%--4.40%), and-6.96% (95% CI:-7.24%--6.68%), respectively. The burden of LRIs remained high among those aged 70 and above, while it was lowest among the 15-<50 age group. The risk of death from LRIs decreased with increasing age. Conclusions From 1990 to 2021, the overall disease burden of LRIs in China declined, but the burden remained significant among children aged 0-<5 years and adults aged 70 and above. Mortality risk was influenced by age, period, and cohort effects.
- Lower respiratory infections,
- Disease burden,
- Trends of change,
- Age-period-cohort model

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References(26)

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