Characterization of nasopharyngeal cancer incidence in Qidong, Jiangsu Province, 1972-2021

WANG Jun; CHEN Yongsheng; ZHU Jian

doi:10.16462/j.cnki.zhjbkz.2025.04.017

Volume 29 Issue 4

Apr. 2025

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WANG Jun, CHEN Yongsheng, ZHU Jian. Characterization of nasopharyngeal cancer incidence in Qidong, Jiangsu Province, 1972-2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(4): 481-486. doi: 10.16462/j.cnki.zhjbkz.2025.04.017

Citation:

WANG Jun, CHEN Yongsheng, ZHU Jian. Characterization of nasopharyngeal cancer incidence in Qidong, Jiangsu Province, 1972-2021[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(4): 481-486. doi: 10.16462/j.cnki.zhjbkz.2025.04.017

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Characterization of nasopharyngeal cancer incidence in Qidong, Jiangsu Province, 1972-2021

doi: 10.16462/j.cnki.zhjbkz.2025.04.017

Department of Etiology, Qidong People′s Hospital, Qidong Liver Cancer Institute, Affiliated Qidong Hospital of Nantong University, Qidong 226200, China

Funds:

Nantong City "14th Five-Year Plan" Science, Education and Health Project Nantong Healthy, Science and Technology [2021] No. 15

2023 Nantong Municipal Health Commission Scientific Research Project MS2023121

More Information

Corresponding author: ZHU Jian, E-mail: jsqdzj8888@sina.com
Received Date: 2024-08-12
Rev Recd Date: 2025-01-02
Publish Date: 2025-04-10

Abstract

Abstract

Objective To analyze the prevalence trend of nasopharyngeal cancer (NPC) incidence in Qidong, Jiangsu Province, from 1972 to 2021, and to provide scientific basis for the prevention and control of nasopharyngeal cancer. Methods The crude incidence rate (CR), age-standardized rate by Segi′s world standard population (ASR-W), 35- < 65-year-old truncated rate and 0- < 75-year-old cumulative incidence rate were calculated from 1972 to 2021. The age-period-cohort model was used to analyze the age, period and cohort effects of incidence in nasopharyngeal cancer Joinpoint regression was performed by using Joinpoint 4.9.1.0 software to calculate the annual percentage change (APC) and average annual percentage change (AAPC) of incidence in nasopharyngeal cancer. Results From 1972 to 2021, Qidong had a total of 1 283 cases of nasopharyngeal cancer. The CR, ASR-W, the truncated rate of 35- < 65 and cumulative rate of 0- < 75 were 2.29/10⁵, 1.65/10⁵, 3.62/10⁵ and 0.18%, respectively. There were 870 cases in male, with CR and ASR-W of 3.15/10⁵ and 2.34/10⁵. In female, there were 413 cases, with CR and ASR-W of 1.45/10⁵ and 0.99/10⁵. Age-period-cohort model showed that age and period effect were the important factors for nasopharyngeal cancer incidence, and the differences were all statistically significant, while cohort effect has no statistically significant. The AAPCs for the both gender, male and female of ASR-W of nasopharyngeal cancer in Qidong from 1972-2021 were 0.14% (95% CI: -0.53%-0.81%, t=0.40), -0.24% (95% CI: -0.86%-0.38%, t=-0.76) and 0.39% (95% CI: -0.89%-1.70%, t=0.60), respectively. None of the differences in trend changes were statistically significant. Conclusions There is no obvious trend in the standardized incidence rate of nasopharyngeal cancer in the past 50 years in Qidong, while has a definite upward trend over the last 20 years. And there are gender and age differences, with the incidence rate of males higher than that of females. The standard incidence is greatly affected by aging, with a high incidence rate in the middle-aged and elderly population. Thus, attention should be paid to prevention and treatment of nasopharyngeal cancer in the middle-aged and elderly population and in males as well as health education.
- Nasopharyngeal cancer,
- Incidence,
- Age-period-cohort model

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References(20)

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