Common influences on chemotherapy-related symptom clusters in cancer patients

MA Dianyu; RONG Xiangxia; SU Chunyan; TONG Jingjing; HONG Shikai; LU Tianya

doi:10.16462/j.cnki.zhjbkz.2025.04.018

Volume 29 Issue 4

Apr. 2025

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2025 > 29(4): 487-491

MA Dianyu, RONG Xiangxia, SU Chunyan, TONG Jingjing, HONG Shikai, LU Tianya. Common influences on chemotherapy-related symptom clusters in cancer patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(4): 487-491. doi: 10.16462/j.cnki.zhjbkz.2025.04.018

Citation:

MA Dianyu, RONG Xiangxia, SU Chunyan, TONG Jingjing, HONG Shikai, LU Tianya. Common influences on chemotherapy-related symptom clusters in cancer patients[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2025, 29(4): 487-491. doi: 10.16462/j.cnki.zhjbkz.2025.04.018

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Common influences on chemotherapy-related symptom clusters in cancer patients

doi: 10.16462/j.cnki.zhjbkz.2025.04.018

1.
Department of Oncology, the First Affiliated Hospital of Anhui University of Science and Technology, Huainan 232007, China
2.
Department of Breast Surgery, the First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, China

Funds:

Anhui Province Medical Science and Technology and Artificial Intelligence Collaborative Innovation Project 23YGXT005

2022 Annual School-level Research Project of Wannan Medical College JXYY2022130

More Information

Corresponding author: MA Dianyu, E-mail: FY2019186@aust.edu.cn
Received Date: 2024-08-26
Rev Recd Date: 2025-01-13
Publish Date: 2025-04-10

Abstract

Abstract

Objective To explore the common influencing factors of chemotherapy-related symptom clusters across different types of cancer. Methods A total of 546 cancer patients (lung cancer, breast cancer, and colorectal cancer) who received chemotherapy the First Affiliated Hospital of Anhui University of Science and Technology from 2022 to 2023 were selected as study subjects. The Anderson Symptom Assessment Scale (MDASI-C) was used to assess the severity of 19 common cancer-related symptoms in the past 24 hours. Patients with an average MDASI-C score ≥7 were classified into the high-symptom group, and those with a score < 7 were into the low-symptom group. Results Univariate analysis revealed that the severity of chemotherapy-related symptom clusters in patients with different cancer types was significantly associated with factors such as gender, age, education level, monthly income per capita, exercise frequency, BMI, time since diagnosis, hemoglobin levels, red blood cell count, blood sodium, and blood potassium (all P < 0.10). After conducting a multivariate logistic regression analysis on all three cancer types, it was found that primary school and below (OR=0.44, 95% CI: 0.27-0.74), low BMI (OR=0.93, 95% CI: 0.88-0.98), and low hemoglobin levels (OR=0.98, 95% CI: 0.97-0.99) were associated with an increased risk of chemotherapy-related symptom clusters. Conclusions Low education level, low BMI, and low hemoglobin levels are significant risk factors for chemotherapy-related symptom clusters in cancer patients. Targeted preventive measures should be implemented before chemotherapy to improve the quality of life of patients after treatment.
- Cancer,
- Chemotherapy,
- Symptom clusters,
- Common influencing factors

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References(8)

References

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