南昌市活禽市场禽流感病毒及从业人员特征分析

谢文静; 胡茂红; 宋文涛; 吴景文; 夏文; 陈盛恩; 陈海婴; 刘明斌

doi:10.16462/j.cnki.zhjbkz.2016.09.011

南昌市活禽市场禽流感病毒及从业人员特征分析

doi: 10.16462/j.cnki.zhjbkz.2016.09.011

1. 南昌大学公共卫生学院流行病学与卫生统计学教研室, 江西南昌 330006;
2. 南昌市疾病预防控制中心传染病防制科, 江西南昌 330038

基金项目:

国家自然科学基金（81460302）；江西省科技计划重大项目（20143ACG70004）

详细信息

作者简介:
谢文静(1987-),女,江西九江人,在读硕士研究生。主要研究方向:传染病流行病学。

中图分类号: R184.39;R181
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出版历程
- 收稿日期: 2016-04-12
- 修回日期: 2016-07-25

Epidemiological characteristics of live poultry markets and poultry related workers in Nanchang

1. Department of Epidemiology and Statistics, School of Public Health, Nanchang University, Nanchang 330006, China;
2. Department of Communicable Disease Control and Prevention, Nanchang Center for Disease Control and Prevention, Nanchang 330038, China

摘要

摘要: 目的了解南昌市活禽市场管理措施实施情况，活禽职业人群的流行病学特征和市场禽流感病毒污染现状。方法采用概率比例规模抽样法（probability proportional to size sampling，PPS）抽取南昌市76家活禽市场及其职业人群作为调查对象。自制问卷收集活禽市场管理措施实施情况、活禽职业人群的人口统计学和职业暴露信息。实时荧光定量RT-PCR检测环境标本禽流感病毒核酸并分型。结果 76家市场中，55.26%（42/76）实施一日一清洗；76.32%（58/76）实行一周一消毒；97.37%（74/76）现场宰杀活禽；69.74%（53/76）活禽存栏过夜。390名从业人员的平均累计职业暴露时间为13.00年（6.12～20.00年），主要暴露方式为宰杀（72.56%）和销售（55.90%）；11.79%近期接触过病死禽。474份环境标本中，75（15.82%）份A型流感病毒核酸阳性，其中H9阳性44份，H5阳性16份，H7阳性11份，H10阳性2份。结论南昌市活禽市场禽流感防控措施未充分落实，市场禽流感病毒污染较为严重，提示需要进一步加强市场防控措施实施力度，降低活禽职业人群和市场顾客的感染风险。
- 禽流感 /
- 环境暴露 /
- 流行病学方法
Abstract: Objective To understand epidemiological characteristics of live poultry markets (LPMs) and related workers, and the contamination status of LPMs in Nanchang. Methods LPMs and poultry related workers were randomly selected as study subjects by using Probability-Proportional-to-Size Sampling. Self-designed questionnaires were used to collect information of LPMs and poultry related workers. Sewage, poultry fresh feces and smears of poultry cage samples were collected to detect subtypes of avian influenza viruses using real-time RT-PCR. Results A total of 76 LPMs and 390 poultry workers were investigated. Of total LPMs, 55.26% (42/76) were cleaned every day, 76.32% (58/76) were sterilized at least one time per week, only two rested for one day per month, 97.37% (74/76) slaughtered poultry and 69.74% (53/76) kept live poultry overnight in markets. The median cumulative time of poultry workers' exposure to live poultry was 13.00 years (inter-quartile range: 6.12 to 20.00 years). Of the 390 poultry workers, 72.56% reported their exposure to live poultry through slaughtering and 55.90% through sale, and 11.79% reported having direct contact with sick or dead poultry recently. 474 environment samples were collected from LPMs. Of these, 75 were positive for influenza A virus, with an overall positive rate of 15.82%. Among these 75 positive samples, 44, 16, 11 and 2 were positive for H9, H5, H7 and H10, respectively. Conclusions The avian influenza control measures were insufficient in LPMs, which were heavily contaminated in Nanchang. Further management of the LPMs should be employed to reduce the infection risk of avian influenza virus for live poultry workers and customers visiting LPMs.
- Influenza in birds /
- Environmental exposure /
- Epidemiologic methods

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参考文献(20)

Chen H, Yuan H, Gao R, et al. Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study [J]. Lancet, 2014,383(9918):714-721.

Liu M, Li X, Yuan H, et al. Genetic diversity of avian influenza A (H10N8) virus in live poultry markets and its association with human infections in China [J]. Sci Rep, 2015,5:7632.

Qi W, Zhou X, Shi W, et al. Genesis of the novel human-infecting influenza A (H10N8) virus and potential genetic diversity of the virus in poultry, China [J]. Euro Surveill, 2014,19(25).pii:20841.

Zhang T, Bi Y, Tian H, et al. Human infection with influenza virus A (H10N8) from live poultry markets, China, 2014 [J]. Emerg Infect Dis, 2014,20 (12):2076-2079.

Liu W, Zhu Y, Qi X, et al. Risk assessment on the epidemics of human infection with a novel avian influenza A (H7N9) virus in Jiangsu Province, China [J]. J Biomed Res, 2013,27(3):163-166.

Chen Y, Liang W, Yang S, et al. Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome [J]. Lancet, 2013,381(9881):1916-1925.

刘社兰,柴程良. 中国人感染H7N9禽流感流行现状与防控对策 [J]. 中华临床感染病杂志, 2013,6(3):132-135.

刘晓青,傅伟杰,谢昀,等. 江西省人感染H7N9禽流感流行病学特征分析 [J]. 中华疾病控制杂志, 2015,19(3):265-268.

Yu H, Wu JT, Cowling BJ, et al. Effect of live poultry market closure in reducing bird-to-human transmission of avian influenza A (H7N9) virus: an ecological study [J]. Lancet, 2014,383(9916):541-548.

Fournié G, Guitian FJ, Mangtani P, et al. Impact of the implementation of rest days in live bird markets on the dynamics of H5N1 highly pathogenic avian influenza [J]. J R Soc Interface, 2011,8(61):1079-1089.

Indriani R, Samaan G, Gultom A, et al. Environmental sampling for avian influenza virus A ( H5N1) in live-bird markets, Indonesia [J]. Emerg Infect Dis, 2010,16(12):1889-1895.

Leung YH, Lau EH, Zhang LJ, et al. Avian influenza and ban on overnight poultry storage in live poultry markets, Hong Kong [J]. Emerg Infect Dis, 2012,18(8): 1339-1341.

Samaan G, Gultom A, Indriani R, et al. Critical control points for avian influenza A H5N1 in live bird markets in low resource set-tings [J]. Prev Vet Med, 2011,100(1):71-78.

叶夏良,雷永良,李羽敏,等. 2009-2015 年浙江省丽水市外环境禽流感病毒监测与分析 [J]. 疾病监测, 2015,30(7):564-569.

赵宗芬,崔小波,王定芬. 2014 年湖北省郧县外环境禽流感病毒监测结果分析 [J]. 职业与健康, 2015,31(14):1952-1953

,1956.

崔小波,赵国兵,梅玉发,等. 2013 年湖北省十堰市禽类职业暴露人群及外环境禽流感病毒监测分析 [J]. 实用预防医学, 2015,22(3):343-344.

Trock SC, Gaeta M, Gonzalez A, et al. Evaluation of routine depopulation, cleaning, and disinfection procedures in live bird markets, New York [J]. Avian Dis, 2008,52(1):160-162.

谭小华,孙立梅,何剑峰,等. 广东省活禽市场管理措施实施现况调查 [J]. 华南预防医学, 2015,41(1):61-64.

Hu M, Li X, Ni X, et al. Coexistence of avian influenza virus H10 and H9 subtypes among chickens in live poultry markets during an outbreak of human infection with novel H10N8 virus in Nanchang, China [J]. Jpn J Infect Dis, 2015,68(5): 364-369.

Ni X, He F, Hu M, et al. Investigation of avian influenza virus in poultry and wild birds due to novel avian-origin influenza A (H10N8) in Nanchang City, China [J]. Microbes Infect, 2015,17(1):48-53.

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