人群两次24小时尿量及食盐摄入量关联性分析

徐建伟; 白雅敏; 刘敏; 陈晓荣; 颜流霞; 吴静

doi:10.16462/j.cnki.zhjbkz.2020.03.007

人群两次24小时尿量及食盐摄入量关联性分析

doi: 10.16462/j.cnki.zhjbkz.2020.03.007

100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心

基金项目: 山东省-卫生部联合减盐防控高血压项目(2013);中国疾病预防控制中心青年科研基金(2018A203)

详细信息

通讯作者:
吴静, E-mail:wujing@ncncd.chinacdc.cn

中图分类号: R151.4;R446.12
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- 文章访问数: 163
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出版历程
- 收稿日期: 2019-07-31
- 修回日期: 2019-11-07
- 刊出日期: 2020-03-10

Analysis of urine volume and dietary salt intake assessed by two 24 hours urine specimens

National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China

Funds: Shandong-Ministry of Health Action on Salt Reduction and Hypertension(2013); Young Scholar Scientific Research Foundation of Chinese Center for Disease Control and Prevention(2018A203)

More Information

Corresponding author: WU Jing, E-mail:wujing@ncncd.chinacdc.cn

摘要

摘要: 目的分析两次24 h尿量和尿盐排出量, 探讨24 h尿用于评估群体和个体食盐摄入量的价值。方法于2013-2014年在山东省和江苏省4个项目县, 采用多阶段整群随机抽样的方法, 抽取18~69岁调查对象进行问卷调查并收集间隔1 d两次24 h尿液, 比较两次24 h尿量的差异, 从个体和群体两个层面分析两次24 h尿盐排出量的差异。结果 1 288名研究对象年龄为(42.3±14.0)岁, 男性626名(48.6%)。24 h平均尿量为(1 462±437)ml, 第1次24 h尿量(1 427±488)ml低于第2次24 h尿量(1 498±552)ml(t=-4.439, P < 0.001)。调查对象每日食盐摄入量为(9.8±3.3)g, 男性每日食盐摄入量(10.1±3.5)g高于女性(9.5±3.1)g(t=3.09, P=0.002), 不同年龄组人群每日食盐摄入量差异有统计学意义(F=7.57, P < 0.001), 1 136名(88.2%)研究对象每日食盐摄入量高于推荐值。从个体层面比较, 调查对象两次24 h尿盐排出量绝对差异 < 1 g, 人数为279(21.7%), 而有48.5%的调查对象差异 > 3 g。从群体层面比较, 调查对象两次24 h尿盐排出量分别为(9.9±4.1)g和(9.7±4.0)g, 差异无统计学意义(P=0.102), 两次24 h尿盐排出量的组内相关系数为0.508(95% CI:0.451~0.559)。结论本研究结果提示24 h尿钠能较好评估人群食盐摄入量, 但不能准确反映个体食盐摄入量。
- 尿量 /
- 盐 /
- 24小时尿
Abstract: Objective To analyze urine volume and dietary salt intake assessed by two 24 h urine specimens, to discuss its application value for evaluating population level and individual level dietary salt intake. Methods The subjects aged 18-69 years were selected from four counties in Shandong Province and Jiangsu Province from 2013 to 2014 by using multi-stage stratified cluster random sampling method. A questionnaire survey was conducted and two 24 h urine with an interval of one day were collected. The differences between two 24 h urine volume, and the dietary salt intake between two 24 h urine were assessed at individual level and population level. Results A total of 1 288 subjects was(42.3±14.0)years old, of which 626(48.6%) were males. The average urine volume of the subjects was(1 462±437) ml. The first 24 h urine volume(1 427±488) ml was lower than the second 24 h urine volume(1 498±552) ml(t=-4.439, P < 0.001). The dietary salt intake was(9.8±3.3) g, and the dietary salt intake of males(10.1±3.5) g was higher than that of females(9.5±3.1) g(t=3.09, P=0.002). There was a significant difference in dietary salt intake among different age groups(F=7.57, P < 0.001). The dietary salt intake of 1 136(88.2%) subjects was higher than the recommended level. At the individual level, the participants with the absolute difference with 1 g between the subjects' two 24 h urinary salt excretion was 279(21.7%), and the participants with the absolute difference with > 3 g was 48.5%. At the population level, the first 24 h urinary salt excretions(9.9 ± 4.1) g was similar to that in the second 24 h urine and(9.7±4.0) g(P=0.1021). The intraclass correlation coefficients between salt excretions in the two 24 h urine was 0.508(95% CI:0.451-0.559). Conclusion The results of this study suggest that 24 h urinary salt excretion can better assess the salt intake at population level, but cannot accurately reflect the individual's salt intake.
- Urine volume /
- Salt /
- 24 h urine

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图 1 调查对象两次24 h尿盐排出量的Bland-Altman图

Figure 1. Bland-Altman plots of two 24-hour urinary salt excretions

下载: 全尺寸图片幻灯片

表 1 调查对象基本情况

Table 1. Baseline characteristics of participants

特征	例数	构成比(%)
性别
男	626	48.6
女	662	51.4
年龄(岁)
18~	301	23.4
30~	558	43.3
50~69	429	33.3
文化程度
小学及以下	486	37.7
初中	528	41.0
高中及以上	274	21.3
职业
农林牧渔劳动者	527	40.9
生产运输工人	211	16.4
家务人员	223	17.3
商业服务业人员	97	7.5
专业技术人员	64	5.0
其他	166	12.9
体重状况
正常	567	44.0
超重	480	37.3
肥胖	241	18.7

下载: 导出CSV

表 2 研究对象两次24 h尿量情况比较

Table 2. Comparison of two 24 h urine volume of participants

变量	平均尿量(ml)	第1次24 h尿量(ml)	第2次24 h尿量(ml)	t值	P值
性别
男	1 504±468	1 470±522	1 538±597	-2.733	0.006
女	1 423±401	1 386±450	1 460±504	-3.627	< 0.001
年龄(岁)
18~	1 328±353	1 325±418	1 330±432	-0.187	0.851
30~	1 482±418	1 443±482	1 522±535	-3.186	0.002
50~69	1 531±491	1 478±530	1 584±622	-3.594	< 0.001
合计	1 462±437	1 427±488	1 498±552	-4.439	< 0.001

下载: 导出CSV

表 3 研究对象两次24 h尿盐排出量情况比较

Table 3. Comparison of two 24-hour urinary salt excretions of study subjects

变量	每日盐摄入量(g)	第1次24 h尿盐排出量(g)	第2次24 h尿盐排出量(g)	t值	P值
性别
男	10.1±3.5	10.3±4.3	9.9±4.1	2.356	0.019
女	9.5±3.1	9.5±3.8	9.5±3.9	-0.024	0.980
年龄(岁)
18~	10.4±3.4	10.6±4.2	10.1±4.1	1.963	0.051
30~	9.8±3.3	9.9±4.1	9.7±4.1	1.284	0.200
50~69	9.4±3.2	9.4±3.9	9.5±3.9	-0.335	0.738
合计	9.8±3.3	9.9±4.1	9.7±4.0	1.636	0.102

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