妊娠中期妇女睡眠时间与正常血压高值的相关性

王晓彤; 唐努; 吴维佳; 潘雯婷; 吕雅杰; 陈丹羽; 代小维; 陈亚军; 静进; 蔡莉

doi:10.16462/j.cnki.zhjbkz.2020.03.017

妊娠中期妇女睡眠时间与正常血压高值的相关性

doi: 10.16462/j.cnki.zhjbkz.2020.03.017

1.
510080 广州, 中山大学公共卫生学院预防医学系
2.
510080 广州, 中山大学公共卫生学院儿少卫生与妇幼保健系
3.
518000 深圳, 深圳市南山区妇幼保健院临床营养科

基金项目: 国家自然科学青年科学基金项目(81602862);深圳市“三名”工程项目(SZSM201803061)

详细信息

通讯作者:
蔡莉, E-mail:caili5@mail.sysu.edu.cn

中图分类号: R714
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出版历程
- 收稿日期: 2019-09-18
- 修回日期: 2020-01-20
- 刊出日期: 2020-03-10

The distribution of sleep duration in mid-pregnancy and its association with prehypertension

1.
Department of Preventive Medicine, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China
2.
School of Maternal and Child Health, Department of Public Health, Sun Yat-sen University, Guangzhou 510080, China
3.
Department of Nutrition, Shenzhen Nanshan Maternity and Child Healthcare Hospital, Shenzhen 518000, China

Funds: National Natural Science Foundation of China(81602862); Sanming Project of Medicine in Shenzhen(SZSM201803061)

More Information

Corresponding author: CAI Li, E-mail:caili5@mail.sysu.edu.cn

摘要

摘要: 目的了解妊娠中期妇女睡眠时间的分布, 探讨其与正常血压高值(prehypertension, PHT)之间的关联。方法选取2017-2018年在广州市某区妇幼保健院进行产检的妊娠20~28周妇女943名。通过面对面问卷调查及医疗档案收集妊娠中期妇女的一般人口学信息、睡眠状况、血压、体重、身高及既往史等资料。采用方差分析和χ²检验比较各组间的睡眠时间差异; 采用多因素Logistic回归分析模型分析睡眠时间与PHT的关联。结果妊娠中期妇女平均每天总睡眠时间为(10.41±1.67)h, 平均夜间睡眠时间为(9.48±1.21)h, 两者分布与年龄、文化程度呈负相关; 总睡眠时间≥7 h/d的比例为98.33%, ≥9 h/d的比例为80.97%;入睡时间点平均为(22:42±1.24), 两者分布与被动吸烟呈负相关; 平均日间睡眠时间为(0.93±0.69)h, 与总体力活动呈正相关。本研究PHT检出率为9.61%;未发现睡眠时间与PHT之间的关联。结论妊娠中期妇女睡眠时间较长, 在不同年龄、文化程度、体力活动、是否被动吸烟者中的分布具有明显差异, 未观察到其睡眠时间与正常血压高值的相关性。
- 妊娠中期 /
- 睡眠时间 /
- 血压
Abstract: Objective To study the distribution of sleep duration in mid-pregnancy women and examine its association with prehypertension(PHT). Methods In the baseline survey of a prospective cohort study, 943 women in mid-pregnancy were recruited in Guangzhou, China in 2017-2018. A standardized questionnaire was used to assess demographic characteristics, sleep duration and other lifestyles. We obtained maternal blood pressure values, weights, heights, and medical histories from medical records. Multivariate logistic regression was conducted to examine the association between sleep duration and PHT. Results The average daily sleep duration of women in mid-pregnancy was(10.41 ± 1.67)hours, and it was negatively related to age and educational level. Overall, 98.33% of pregnant women had a daily sleep duration ≥ 7 h and the distribution was related to passive smoking. The average night time sleep duration was(9.48±1.21)hours, and it was negatively related to age and educational level. The daytime sleep duration was(0.93 ± 0.69)hours, and it was positively associated with physical activity. The average bedtime was(22:42 ± 1.24), and it was positively associated with passive smoking. The prevalence of PHT was 9.61%. We did not observe any significant association between sleep duration and PHT. Conclusions The mid-pregnancy women in Guangzhou had relatively long sleep duration, and it differed by maternal age, educational level, physical activity, and passive smoking. There was no significant association between sleep duration and PHT.
- Women in mid-pregnancy /
- Sleep duration /
- Prehypertension

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表 1 妊娠中期妇女睡眠时间分布情况(x±s)

Table 1. The distribution of total sleep duration of women in mid-pregnancy(x±s)

变量	平均睡眠时间(x±s)	t/F值	P值
年龄(岁)		2.07	0.038
非高龄(< 35)	10.44±1.65
高龄(≥35)	10.14±1.72
文化程度		7.84	0.004
小学及初中	10.86±2.10
高中及大专	10.36±1.62
大学及以上	10.22±1.43
民族		0.52	0.606
非汉族	10.54±1.93
汉族	10.38±1.66
被动吸烟		1.01	0.331
无	10.42±1.62
有	10.30±1.78
家庭人均月收入(元)		0.86	0.463
≤4 000	10.36±1.90
4 001~	10.48±1.65
8 001~	10.43±1.44
> 12 000	10.25±1.62
体力活动		1.17	0.312
T1	10.37±1.65
T2	10.29±1.60
T3	10.49±1.72
膳食能量摄入		0.68	0.505
T1	10.32±1.76
T2	10.38±1.68
T3	10.48±1.55	.
孕前BMI分类		1.37	0.171
正常或偏瘦	10.42±1.64
超重或肥胖	10.19±1.79
正常血压高值		-0.73	0.463
否	10.38±1.66
是	10.51±1.64
注:T1、T2、T3表示分别对体力活动和膳食能量摄入进行三等划分后的低、中、高组。

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表 2 妊娠中期妇女睡眠时间分布情况

Table 2. The distribution of total sleep duration of women in mid-pregnancy

变量	过短(%)	适中(%)	过长(%)	χ²值	P值
年龄(岁)				2.86	0.239
非高龄(< 35)	1.56	16.62	81.82
高龄(≥35)	2.44	21.34	76.22
文化程度				3.20	0.525
小学及初中	2.00	16.67	81.33
高中及大专	1.27	19.20	79.54
大学及以上	2.26	15.16	82.58
民族				0.76	0.685
非汉族	3.57	14.29	82.14
汉族	1.67	17.69	80.65
被动吸烟				8.95	0.011
无	1.16	16.06	82.78
有	3.29	21.40	75.31
家庭人均月收入(元)				9.93	0.127
≤4 000	3.19	20.74	76.06
4 001~	0.87	15.07	84.06
8 001~	0.57	17.14	82.29
> 12 000	2.65	18.58	78.76
体力活动				2.11	0.715
T1	1.62	16.50	81.88
T2	2.25	18.65	79.10
T3	0.98	17.65	81.37
膳食能量摄入				7.49	0.112
T1	1.35	22.22	76.43
T2	1.69	16.89	81.42
T3	1.35	13.85	84.80
孕前BMI分类				5.11	0.079
正常或偏瘦	1.27	16.90	81.83
超重或肥胖	3.48	21.74	74.78
正常血压高值				1.20	0.550
否	1.66	17.87	80.47
是	2.25	13.48	84.27

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表 3 妊娠中期妇女夜间睡眠和日间睡眠时间分布情况(x±s)

Table 3. The distribution of nighttime and daytime sleep duration of women in mid-pregnancy(x±s)

变量	夜间睡眠时间(x±s)h/d	t/F值	P值	日间睡眠时间(x±s)h/d	t/F值	P值	夜间入睡时间点(x±s)24 h制	t/F值	P值
年龄(岁)		2.43	0.015		0.44	0.662		1.35	0.179
非高龄(< 35)	9.51±1.20			0.92±0.68			22:44±1.29
高龄(≥35)	9.26±1.20			0.90±0.72			22:34±0.58
文化程度		11.59	< 0.001		1.59	0.205		0.89	0412
小学及初中	9.85±1.47			1.00±0.86			22:48±1.41
高中及大专	9.47±1.18			0.90±0.68			22:43±1.28
大学及以上	9.28±1.06			0.92±0.57			22:37±1.06
民族		0.81	0.416		-0.15	0.884		0.48	0.633
非汉族	9.64±1.51			0.89±0.69			22:50±1.15
汉族	9.46±1.20			0.92±0.68			22:42±1.25
被动吸烟		1.36	0.1748		0.16	0.873		-2.69	0.008
有	9.37±1.30			0.91±0.72			22:54±1.23
无	9.50±1.17			0.92±0.67			22:37±1.24
家庭人均月收入(元)		1.62	0.184		0.56	0.639		1.02	0.384
≤4000	9.48±1.39			0.88±0.74			22:41±1.26
4 001~	9.58±1.22			0.92±0.69			22:46±1.22
8 001~	9.47±1.00			0.97±0.64			22:32±1.31
> 12 000	9.33±1.18			0.90±0.65			22:42±1.20
体力活动		0.65	0.523		3.19	0.042		0.03	0.968
T1	9.49±1.23			0.87±0.64			22:41±1.38
T2	9.40±1.17			0.87±0.66			22:43±1.07
T3	9.50±1.22			1.00±0.73			22:41±1.25
膳食能量摄入		0.43	0.649		1.69	0.185		0.31	0.732
T1	9.45±1.29			0.86±0.71			22:46±1.29
T2	9.43±1.17			0.94±0.72			22:41±1.32
T3	9.52±1.16			0.95±0.62			22:41±1.12
孕前BMI分类		0.82	0.414		1.67	0.096		0.39	0.696
正常或偏瘦	9.48±1.20			0.93±0.68			22:43±1.23
超重或肥胖	9.38±1.30			0.82±0.67			22:39±1.33
正常血压高值		-0.55	0.582		-0.89	0.374		0.08	0.940
否	9.46±1.21			0.91±0.68			22:42±1.26
是	9.53±1.22			0.97±0.62			22:41±1.06

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表 4 妊娠中期妇女不同睡眠时间与PHT关系的Logistic回归分析模型

Table 4. Logistic regression analysis of sleep duration and PHT

变量	时长(h)	PHT(95% CI)值(%)	模型1		模型2		模型3
变量	时长(h)	PHT(95% CI)值(%)	OR(95% CI)值	P值	OR(95% CI)值	P值	OR(95% CI)值	P值
总睡眠时间(h)
T1	8.67± 0.75	9.40(6.39~12.97)	1.20(0.69~2.09)	0.458	1.21(0.69~2.11)	0.454	1.12(0.62~2.01)	0.689
T2	10.31± 0.43	7.96(4.98~10.99)	1.00	-	1.00	-	1.00	-
T3	12.27 ± 1.04	11.15(7.67~14.77)	1.45(0.84~2.49)	0.532	1.41(0.82~2.44)	0.607	1.27(0.71~2.26)	0.679
夜间睡眠时间(h)
T1	8.22 ± 0.64	8.60(5.59~11.89)	0.95(0.56~1.65)	0.848	0.95(0.54~1.68)	0.854	0.96(0.53~1.73)	0.867
T2	9.41 ± 0.28	9.03(5.94~12.42)	1.00	-	1.00	-	1.00	-
T3	10.79 ± 0.76	10.83(7.44~14.36)	1.22(0.72~2.07)	0.367	1.18(0.69~2.00)	0.443	1.21(0.68~2.14)	0.443
日间睡眠时间(h)
T1	0.20 ± 0.22	6.96(4.41~10.14)	0.70(0.40~1.23)	0.215	0.70(0.40~1.23)	0.203	0.71(0.39~1.30)	0.248
T2	0.91 ± 0.13	8.65(6.76~13.37)	1.00	-	1.00	-	1.00	-
T3	1.71 ± 0.47	11.00(7.96~15.32)	1.18(0.71~1.97)	0.067	1.17(0.70~2.94)	0.071	1.09(0.63~1.90)	0.166
注:模型1未调整; 模型2调整年龄(连续变量)、孕前BMI(超重、非超重); 模型3调整年龄(连续变量)、孕前BMI(超重、非超重)、孕周(连续变量)、文化程度(小学及初中、高中及大专、大学及以上)、月收入(≤4 000元、4 001~元、8 001~元、 > 12 000元)、职业(商业、服务业人员、管理人员和职员、家务或者待业、其他)、民族(汉族、非汉族)、被动吸烟(是、否)、总体力活动(三等分)、总膳食能量摄入(三等分)。

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变量	平均睡眠时间(x±s)	t/F值	P值
年龄(岁)		2.07	0.038
非高龄(< 35)	10.44±1.65
高龄(≥35)	10.14±1.72
文化程度		7.84	0.004
小学及初中	10.86±2.10
高中及大专	10.36±1.62
大学及以上	10.22±1.43
民族		0.52	0.606
非汉族	10.54±1.93
汉族	10.38±1.66
被动吸烟		1.01	0.331
无	10.42±1.62
有	10.30±1.78
家庭人均月收入(元)		0.86	0.463
≤4 000	10.36±1.90
4 001~	10.48±1.65
8 001~	10.43±1.44
> 12 000	10.25±1.62
体力活动		1.17	0.312
T1	10.37±1.65
T2	10.29±1.60
T3	10.49±1.72
膳食能量摄入		0.68	0.505
T1	10.32±1.76
T2	10.38±1.68
T3	10.48±1.55	.
孕前BMI分类		1.37	0.171
正常或偏瘦	10.42±1.64
超重或肥胖	10.19±1.79
正常血压高值		-0.73	0.463
否	10.38±1.66
是	10.51±1.64
注:T1、T2、T3表示分别对体力活动和膳食能量摄入进行三等划分后的低、中、高组。

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妊娠中期妇女睡眠时间与正常血压高值的相关性

doi: 10.16462/j.cnki.zhjbkz.2020.03.017

通讯作者:
蔡莉, E-mail:caili5@mail.sysu.edu.cn

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The distribution of sleep duration in mid-pregnancy and its association with prehypertension

Corresponding author: CAI Li, E-mail:caili5@mail.sysu.edu.cn

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妊娠中期妇女睡眠时间与正常血压高值的相关性

doi: 10.16462/j.cnki.zhjbkz.2020.03.017

通讯作者: 蔡莉, E-mail:caili5@mail.sysu.edu.cn

计量

出版历程

The distribution of sleep duration in mid-pregnancy and its association with prehypertension

Corresponding author: CAI Li, E-mail:caili5@mail.sysu.edu.cn

计量

出版历程

目录

通讯作者:
蔡莉, E-mail:caili5@mail.sysu.edu.cn