Awareness, treatment and control of high blood pressure and its determinants in the aged patients with hypertension of Nu ethnic group: a multilevel model analysis
-
摘要:
目的 了解怒族老年高血压人群的高血压知晓、治疗和控制现状,探讨其影响因素。 方法 采用多阶段抽样方法随机抽取1 080名怒族老年人,采用问卷调查和体格检查方法进行现况调查。 结果 1 080名调查对象中检出高血压患者319例,其高血压知晓率、治疗率和控制率分别为38.6%、25.7%和10.3%。其中,男性分别为44.4%、30.0%和15.0%,女性分别为32.7%、21.4%和5.7%;经济发展水平中等地区分别为48.9%、33.2%和14.2%,经济发展水平较低地区分别为23.3%、14.7%和4.7%。与对照组比较,经济发展水平中等地区和中度医疗负担老年高血压人群的知晓率(48.9%vs.23.3%, 42.9%vs.27.1%)、治疗率(33.2%vs.14.7%, 30.0%vs.12.9%)和控制率(14.2%vs.4.7%, 12.9%vs.2.9%)较高;男性老年高血压人群知晓率和控制率(44.4%vs.32.7%, 15.6%vs.5.0%)较高;血脂异常老年高血压人群的知晓率和治疗率(100.0%vs.36.4%, 54.6%vs.24.7%)较高。控制协变量的多层Logistic回归分析模型结果显示,经济发展水平与男性对知晓率、治疗率和控制率有跨层交互作用(均有P<0.05),个体水平协变量血脂异常对知晓率(OR=5.191, 95% CI: 3.141~8.578, P=0.042)、治疗率(OR=6.101, 95% CI: 3.120~11.930, P=0.043)和控制率(OR=6.699, 95% CI: 4.625~9.702, P=0.047)均有正效应,而低盐饮食(OR=0.329, 95% CI: 0.134~0.810, P=0.019)对知晓率有负效应。 结论 怒族老年高血压患者知晓率、治疗率和控制率低于全国水平,主要影响因素为男性、经济发展水平、血脂异常和低盐饮食等。 Abstract:Objective To identify the status of awareness, treatment and control of high blood pressure in the aged patients with hypertension of Nu ethnic group, and to determine the associated determinants. Methods A sample of 1 080 persons, which was sampled by the multiple-stage sampling method from the aged population of Nu ethnic group, was investigated and examined cross-sectionally. Results There were 319 patients with hypertension in the 1 080 participants. The rate of awareness, treatment and control of high blood pressure in the whole patients was 38.6%, 25.7% and 10.3%; that in male patients was 44.4%, 30.0% and 15.0%; that in female patients was 32.7%, 21.4% and 5.7%; that in the middle-economic level area was 48.9%, 33.2% and 14.2%; and that in the low-economic level area was 23.3%, 14.7% and 4.7%, respectively. Comparison to the control groups, the aged patients with hypertension resided in the middle-economic area and those with middle medical burden had a higher awareness rate (48.9% vs. 23.3%, 42.9% vs.27.1%), treatment rate (33.2% vs.14.7%, 30.0% vs.12.9%) and control rate (14.2% vs. 4.7%, 12.9% vs.2.9%); the male patients with hypertension had a greater awareness rate and control rate (44.4% vs.32.7%, 15.6% vs.15.0%); the patients with dyslipidemia and hypertension had a larger awareness rate and treatment rate (100.0% vs.36.4%, 54.6% vs.24.70%). The results of covariate-adjusted multilevel logistic regression model indicated that there was cross-level interaction, which was between economic level and male, on the rates of awareness, treatment and control (all P < 0.05). Dyslipidemia, which was an individual covariate, had a positive effect on the rate of awareness (OR=5.191, 95% CI: 3.141-8.578, P=0.042), treatment (OR=6.101, 95% CI: 3.120-11.930, P=0.043) and control (OR=6.699, 95% CI: 4.625-9.702, P=0.047), respectively. Low salt diet, however, had a negative effect on the rate of awareness (OR=0.329, 95% CI: 0.134-0.810, P=0.019). Conclusions The rates of awareness, treatment and control of high blood pressure in the aged patients with hypertension of Nu ethnic group were lower than those of national population. The dominant determinants were male, economic level, dyslipidemia and low salt diet, etc. -
Key words:
- Nu ethnic group /
- Hypertension /
- Awareness rate /
- Treatment rate /
- Control rate /
- Multilevel model
-
表 1 不同特征怒族老年高血压人群的知晓率比较[n(%)]
Table 1. Comparison of the awareness rate among the elderly hypertension population of Nu ethnic with different characteristics[n(%)]
变量 调查人数 知晓情况 χ2值 P值 性别 4.585 0.032 男 160 71(44.4) 女 159 52(32.7) 医疗负担 8.637 0.013 轻度 70 19(27.1) 中度 240 103(42.9) 重度 1 1(11.1) 血脂异常 21.597 < 0.001 是 11 11(100.0) 否 308 112(36.4) 经济发展水平中等 21.407 < 0.001 是 190 93(48.9) 否 129 30(23.3) 表 2 不同特征怒族老年高血压人群的治疗率比较[n(%)]
Table 2. Comparison of the treatment rate among the elderly hypertension population of Nu ethnic with different characteristics[n(%)]
变量 调查人数 知晓情况 χ2值 P值 性别 3.100 0.078 男 160 48(30.0) 女 159 34(21.4) 医疗负担 9.372 0.009 轻度 70 9(12.9) 中度 240 72(30.0) 重度 1 1(11.1) 血脂异常 4.962 0.026 是 11 6(54.5) 否 308 76(24.7) 经济发展水平中等 13.664 < 0.001 是 190 63(33.2) 否 129 19(14.7) 表 3 不同特征怒族老年高血压人群的控制率比较[n(%)]
Table 3. Comparison of the control rate among the elderly hypertension population of Nu ethnic with different characteristics[n(%)]
变量 调查人数 知晓情况 χ2值 P值 性别 9.650 0.002 男 160 25(15.6) 女 159 8(5.0) 医疗负担 6.982 0.031 轻度 70 2(2.9) 中度 240 31(12.9) 重度 1 0(0.0) 经济发展水平中等 7.570 0.006 是 190 27(14.2) 否 129 6(4.7) 表 4 高血压知晓率与影响因素关系的多层Logistic回归分析模型
Table 4. Logistic regression model of hypertension awareness rate and influencing factors
参数 β值 sx t值 P值 OR(95% CI)值 截距 -2.750 7 1.174 5 -2.34 0.035 0.064(0.005, 0.793) 经济发展水平 1.019 4 0.256 1 1.35 0.199 2.772(1.600, 4.801) 男性 0.009 7 0.482 0 0.02 0.984 1.010(0.359, 2.839) 经济发展水平×男性 1.449 1 0.201 3 2.41 0.030 4.259(2.766, 6.559) 饮酒 0.978 6 0.558 0 1.75 0.101 2.661(0.804, 8.806) 血脂异常 1.646 9 0.234 2 2.24 0.042 5.191(3.141, 8.578) 年龄组 0.124 1 0.126 0 0.99 0.341 1.132(0.864, 1.484) 有配偶 -0.026 9 0.329 1 -0.08 0.936 0.973(0.481, 1.972) 医疗负担 -0.009 2 0.357 3 -0.03 0.980 0.991(0.460, 2.132) 家庭经济状况 0.511 3 0.375 5 1.36 0.195 1.667(0.745, 3.731) 糖尿病 0.935 1 0.250 6 1.44 0.173 2.547(1.488, 4.361) 低盐饮食 -1.111 8 0.419 8 -2.65 0.019 0.329(0.134, 0.810) 注:变量:经济发展水平(较低=0,中等=1),医疗负担(轻度=1,中度=2,重度=3),年龄组(60~岁=1、65~岁=2、70~岁=3、75~岁=4、80~岁=5),家庭经济状况(差=1,中=2,好=3),血脂异常、男性、饮酒、有配偶、糖尿病和低盐饮食(否=0,是=1)。年龄组、医疗负担、家庭经济状况等有序多分类变量经“相邻两个等级总体OR齐性检验”,差异均无统计学意义(均有P>0.05),即相邻两级总体OR相同,满足线性假设,均可直接引入模型。 表 5 高血压治疗率与影响因素关系的多层Logistic回归分析模型
Table 5. Logistic regression model of hypertension treatment rate and influencing factors
参数 β值 sx t值 P值 OR(95% CI)值 截距 -3.407 8 1.368 1 -2.49 0.026 0.033(0.002, 0.623) 经济发展水平 0.730 3 0.301 6 0.91 0.378 2.076(1.087, 3.964) 男性 -0.452 5 0.563 7 -0.80 0.436 0.636(0.190, 2.131) 经济发展水平×男性 1.506 2 0.278 4 2.22 0.043 4.510(2.482, 8.194) 饮酒 0.946 4 0.576 8 1.64 0.123 2.576(0.748, 8.878) 血脂异常 1.808 5 0.312 6 2.23 0.043 6.101(3.120, 11.930) 年龄组 -0.081 3 0.140 2 -0.58 0.571 0.922(0.682, 1.245) 有配偶 -0.081 7 0.361 8 -0.23 0.825 0.922(0.424, 2.002) 医疗负担 -0.088 7 0.407 1 -0.22 0.831 0.915(0.382, 2.191) 家庭经济状况 0.373 1 0.402 8 0.93 0.370 1.452(0.612, 3.446) 糖尿病 0.338 0 0.750 3 0.45 0.659 1.402(0.280, 7.010) BMI等级 0.122 9 0.216 8 0.57 0.580 1.131(0.710, 1.800) 低盐饮食 0.009 7 0.463 8 0.02 0.984 1.010(0.373, 2.731) 注:变量:经济发展水平(较低=0,中等=1),医疗负担(轻度=1,中度=2,重度=3),年龄组(60~岁=1、65~岁=2、70~岁=3、75~岁=4、80~岁=5),家庭经济状况(差=1,中=2,好=3),BMI等级(体重过低=1,体重正常=2,超重=3,肥胖=4),血脂异常、男性、饮酒、有配偶、糖尿病和低盐饮食(否=0,是=1)。注:医疗负担、家庭经济状况、BMI等级等有序多分类变量经“相邻两个等级总体OR齐性检验”,差异均无统计学意义(均有P>0.05),即相邻两级总体OR相同,满足线性假设,均可直接引入模型。 表 6 高血压控制率与影响因素关系的多层Logistic回归分析模型
Table 6. Logistic regression model of hypertension control rate and influencing factors
参数 β值 sx t值 P值 OR(95% CI)值 截距 -3.985 2 1.742 7 -2.29 0.038 - 经济发展水平 -0.113 2 0.542 7 -0.08 0.934 0.893(0.279, 2.860) 男性 -1.161 3 1.549 9 -0.93 0.369 0.313(0.021, 4.570) 经济发展水平×男性 3.898 7 0.039 3 2.71 0.017 49.338(45.350, 53.678) 年龄组 -0.055 4 0.205 2 -0.27 0.791 0.946(0.609, 1.469) 血脂异常 1.901 9 0.172 7 2.18 0.047 6.699(4.625, 9.702) 有配偶 -0.534 5 0.534 7 -1.00 0.334 0.586(0.186, 1.844) 家庭经济状况 0.050 8 0.584 7 0.09 0.932 1.052(0.300, 3.687) BMI等级 0.088 0 0.363 3 0.24 0.812 1.092(0.501, 2.380) 低盐饮食 0.074 8 0.868 5 0.09 0.933 1.078(0.167, 6.942) 变量:经济发展水平(较低=0,中等=1),家庭经济状况(差=1,中=2,好=3),年龄组(60~岁=1、65~岁=2、70~岁=3、75~岁=4、80~岁=5),BMI等级(体重过低=1,体重正常=2,超重=3,肥胖=4),血脂异常、男性、有配偶和低盐饮食(否=0,是=1)。年龄组、家庭经济状况、BMI等级等有序多分类变量经“相邻两个等级总体OR齐性检验”,差异均无统计学意义(均有P>0.05),即相邻两级总体OR相同,满足线性假设,均可直接引入模型。 -
[1] 王否, 顾佳怡, 徐辉, 等.社区综合健康管理对老年高血压患者生活质量的影响[J].中华疾病控制杂志, 2018, 22(7):708-716. DOI: 10.16462/j.cnki.zhjbkz.2018.07.013.Wang F, Gu JY, Xu H, et al. Effect of community comprehensive health management on quality of life in elderly hypertensive patients[J]. Chin J Dis Prev, 2018, 22(7):708-716. DOI: 10.16462/j.cnki.zhjbkz.2018.07.013. [2] 张永军, 徐尚银, 吴祝霞, 等.动态血压监测指标指导临床治疗老年高血压的意义[J].中华疾病控制杂志, 2019, 23(7):785-789. DOI:10.16462 /j.cnki.zhjbkz.2019.07.009.Zhang YJ, Xu SY, Wu ZX, et al. Guiding value of ambulatory blood pressure monitoring index in clinical prevention and treatment of elderly hypertensive population[J]. Chin J Dis Control Prev, 2019, 23(7):785-789. DOI:10.16462 /j.cnki.zhjbkz.2019.07.009. [3] Lv X, Niu H, Qu Y, et al. Awareness, treatment and control of hypertension among hypertensive patients aged 18 to 59 years old in the northeast of China[J]. SCI Rep, 2018, 8(1):17019. DOI: 10.1038/s41598-018-34923-5. [4] Yang ZQ, Zhao Q, Jiang P, et al. Prevalence and control of hypertension among a community of elderly population in Changning District of Shanghai: a cross-sectional study[J]. BMC Geriatr, 2017, 17(1):296. DOI: 10.1186/s12877-017-0686-y. [5] 李岩岩, 沈寅虎, 秦献辉, 等.连云港农村社区高血压知晓率、服药率和控制率现状研究[J].中华疾病控制杂志, 2011, 15(2): 98-100. http://zhjbkz.ahmu.edu.cn/article/id/JBKZ201102002Li YY, Shen YH, Qin XH, et al. Research on hypertension awareness, treatment, and control rates among adults in Lianyungang rural communities[J]. Chin J Dis Control Prev, 2011, 15(2): 98-100. http://zhjbkz.ahmu.edu.cn/article/id/JBKZ201102002 [6] 宋佳丽, 杨静玮, 张丹薇, 等.我国华中地区三省年龄35-75岁成人高血压知晓、治疗和控制情况[J].中国高血压杂志, 2019, 27(11):1054-1060. DOI: 10.16439/j.cnki.1673-7245.2019.11.016.Song JL, Yang JW, Zhang DW, et al. Awareness, treatment and control rates of hypertension in adults ages 35-75 years in three provinces of central China[J]. Chin J Hypertens, 2019, 27(11):1054-1060. DOI: 10.16439/j.cnki.1673-7245.2019.11.016. [7] Li H, Yan X, Deng X, et al. A cross-sectional study of the prevalence, awareness, treatment and control of hypertension in Shenzhen, China[J]. BMJ Open, 2017, 7(6):e015206. DOI: 10.1136/bmjopen-2016-015206. [8] 国务院人口普查办公室, 国家统计局人口和就业统计司.中国2010年人口普查资料[M].北京:中国统计出版社, 2016:150-165.Census Office of the State CounCIl, Division of Population and Employment Statistics, National Bureau of Statistics. Data from China's 2010 population census[M]. Beijing:China Statistics Press, 2016:150-165. [9] 王卓群, 赵文华.我国慢性病防控工作回顾与展望[J].中华疾病控制杂志, 2019, 23(9):1025-1028. DOI:10.16462 /j.cnki.zhjbkz.2019.09.001.Wang ZQ, Zhao WH. Review and prospect of chronic noncommunicable disease control and prevention in China[J]. Chin J Dis Control Prev, 2019, 23(9):1025-1028. DOI: 10.16462 /j.cnki.zhjbkz.2019.09.001. [10] 中国高血压防治指南修订委员会, 高血压联盟(中国), 中华医学会心血管病学分会, 等.中国高血压防治指南(2018年修订版)[J].中国心血管杂志, 2019, 24(1):24-56. DOI: 10.3969/j.issn.1007-5410.2019.01.002.Writing Group of 2018 Chinese Guidelines for the Management of Hypertension, Chinese Hypertension League, Chinese SoCIety of Cardiology, et al. 2018 Chinese guidelines for the management of hypertension[J]. Chin J Cardiovasc Med, 2019, 24(1):24-56. DOI: 10.3969/j.issn.1007-5410.2019.01.002. [11] 国际生命科学学会中国办事处中国肥胖问题工作组联合数据汇总分析协作组.中国成人体质指数分类的推荐意见简介[J].中华预防医学杂志, 2001, 35(5):349-350. doi: 10.3760/j:issn:0253-9624.2001.05.019International SoCIety for Life SCIences China Office, China Obesity Working Group, Joint Data collection and analysis group. A brief introduction to recommendations for body mass index classification in Chinese adults[J]. Chin J Prev Med, 2001, 35(5):349-350. doi: 10.3760/j:issn:0253-9624.2001.05.019 [12] 于淼, 王建辉, 董建秀, 等.冠心病患者低盐低脂饮食现状及其影响因素[J].现代预防医学, 2019, 46(20):3700-3703, 3718. http://www.cnki.com.cn/Article/CJFDTotal-XDYF201920013.htmYu M, Wang JH, Dong JX, et al. The status of low-salt and low-fat diet and its influencIng factors in patients with coronary heart disease[J]. Modern Preventive Medicine, 2019, 46(20):3700-3703, 3718. http://www.cnki.com.cn/Article/CJFDTotal-XDYF201920013.htm [13] 郑苏梨, 蔡晓琪, 苏津自, 等.做好慢性病预防控制质控工作, 助力提高高血压的知晓率、治疗率和控制率[J].中华高血压杂志, 2019, 27(12):1119-1121. DOI:10.16439/j.cnki.1673- 7245.2019.12.007.Zheng SL, Cai XQ, SU JZ, et al. We will do a good job in the prevention, control and quality control of chronic diseases, and help improve the awareness, treatment and control rates of hypertension[J]. Chin J Hypertens, 2019, 27(12):1119-1121. DOI: 10.16439/j.cnki.1673-7245.2019.12.007. [14] 马丽媛, 吴亚哲, 陈伟伟. 《中国心血管病报告2018》要点介绍[J].中华高血压杂志, 2019, 27(8):712-716. DOI: 10.16439/j.cnki.1673-7245.2019.08.006.Ma LY, Wu YZ, Chen WW. Key points of China cardiovascular Disease Report 2018[J]. Chin J Hypertens, 2019, 27(8):712-716. DOI: 10.16439/j.cnki.1673-7245.2019.08.006. [15] Potts H, Baatarsuren U, Myanganbayar M, et al. Hypertension prevalence and control in Ulaanbaatar, Mongolia[J]. J Clin Hypertens (Greenwich), 2020. DOI: 10.1111/jch.13784. [16] Carey RM, Muntner P, Bosworth HB, et al. Prevention and Control of Hypertension: JACC Health Promotion Series[J]. J Am Coll Cardiol, 2018, 72(11):1278-1293. DOI: 10.1016/j.jacc.2018.07.008. [17] 严小芳, 杨静玮, 白雪珂, 等.华东地区64万成年人高血压知晓、治疗和控制情况[J].中华流行病学杂志, 2020, 41(1):68-73. DOI: 10.3760/cma.j.issn.0254-6450.2020.01.013.Yan XF, Yang JW, Bai XK, et al. Awareness, treatment and control of hypertension in 64 000 adults in eastern China[J]. Chin J Epidemiol, 2020, 41(1):68-73. DOI: 10.3760/cma.j.issn.0254-6450.2020.01.013. [18] 郭杰, 余灿清, 吕筠, 等.中国10个地区人群高血压患病率、知晓率、治疗率和控制情况分析[J].中华高血压杂志, 2016, 37(4):469-474. http://www.cnki.com.cn/Article/CJFDTOTAL-ZGGZ201703035.htmGuo J, Yu CQ, Lu J, et al. Prevalence, awareness, treatment and control rate of hypertension in 10 regions of China[J]. Chin J Epidemiol, 2016, 37(4):469-474. http://www.cnki.com.cn/Article/CJFDTOTAL-ZGGZ201703035.htm [19] 张丹薇, 杨静玮, 崔建兰, 等.中国西南五省高血压患病、知晓、治疗和控制地区比较[J].中国公共卫生, 2019, 35(10):1293-1297. DOI: 10.11847/zgggws1124810.Zhang DW, Yang JW, Cui JL, et al. Regional differences in prevalence, awareness, treatment, and control of hypertension among five provinces in southwest China[J]. Chin J Public Health, 2019, 35(10):1293-1297. DOI: 10.11847/zgggws1124810. [20] 田梦圆, 王小磊, 王皓人, 等.湘西少数民族地区高血压知晓率、治疗率和控制率现状及其影响因素[J].中华疾病控制杂志, 2020, 24(6):676-681. DOI: 10.16462/j.cnki.zhjbkz.2020.06.011.Tian MY, Wang XL, Wang HR, et al. Awareness rate, treatment rate, and control rate of hypertension and its influencing factors in Xiangxi minority areas[J]. Chin J Dis Control Prev, 2020, 24(6):676-681. DOI: 10.16462/j.cnki.zhjbkz.2020.06.011. [21] 汪晓慧, 李剑波, 杨洋.成都市>35岁流动人口高血压患病率、知晓率、治疗率与控制情况分析[J].现代预防医学, 2020, 47(17):3217-3219, 3242. https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFD&filename=XDYF202017039Wang XH, Li JB, Yang Y. Prevalence, awareness, treatment and control of hypertension among migrant population, Chengdu[J]. Modern Preventive Medicine, 2020, 47(17):3217-3219, 3242. https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFD&filename=XDYF202017039 [22] 付朝红, 高莉, 祖晓堋, 等. 2018年郑州市年龄40-79岁居民高血压患病率、知晓率、治疗率与控制率现状[J].中华高血压杂志, 2020, 28(7):646-652. DOI: 10.16439/j.cnki.1673-7245.2020.07.011.Fu CH, Gao L, Zu XP, et al. The rates of hypertension prevalence, awareness, treatment and control among residents aged 40-79 years in Zhengzhou City[J]. Chin J Hypertens, 2020, 28(7):646-652. DOI: 10.16439/j.cnki.1673-7245.2020.07.011. [23] Khanal MK, Dhungana RR, Bhandari P, et al. Prevalence, associated factors, awareness, treatment, and control of hypertension: Findings from a cross sectional study conducted as a part of a community based intervention trial in Surkhet, Mid-western region of Nepal[J]. PLoS One, 2017, 12(10):e0185806. DOI: 10.1371/journal.pone.0185806. [24] 佟明坤, 满塞丽麦, 金成, 等.千万例体检人群高血压患病率、知晓率、治疗率和控制率的调查[J].中国循环杂志, 2020, 35(9):866-872. DOI: 10.3969/j.issn.1000-3614.2020.09.004.Tong MK, Man SLM, Jin C, et al. Prevalence, awareness, treatment and control of hypertension in China: survey on a 10 million health check-up population[J]. Chin Circul J, 2020, 35(9):866-872. DOI: 10.3969/j.issn.1000-3614.2020.09.004.