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摘要:
目的 分析2008―2018年深圳市居民脑卒中发病情况和变化趋势,为制定和评估深圳市脑卒中防治策略提供依据。 方法 利用深圳市居民脑卒中监测数据资料,采用趋势检验和年度变化百分比(annual percent change, APC)分析脑卒中时间变化趋势。 结果 2008―2018年深圳市居民脑卒中年均粗发病率为215.48/10万,APC为1.12%,变化无统计学意义(t=2.07, P=0.07)。男性脑卒中发病率为237.89/10万,高于女性的191.30/10万。0~<45岁年龄组发病率处于较低水平,≥45岁时发病率开始迅速上升。发病率随着年龄的增加而上升,≥75岁年龄组发病率呈现上升趋势,APC为2.75%,差异有统计学意义(t=4.65, P < 0.001)。 结论 2008―2018年深圳市居民脑卒中发病率较为稳定,但高年龄组发病率呈现上升趋势,应进一步关注老年人脑卒中发病情况。 Abstract:Objective To analyze the incidence and trend of stroke in Shenzhen from 2008 to 2018, in order to provide evidence for formulating and evaluating prevention strategy of stroke in Shenzhen. Methods According to stroke monitoring data, the temporal trends of stroke in Shenzhen was analyzed by trend test and annual percentage change (APC). Results From 2008 to 2018, the incidence rate of stroke was 215.48/100 000, with 1.12% APC, and there was no statistical difference in incidence rate of stroke in each year(t=2.07, P=0.07). The incidence rate of male (237.89/100 000) was higher than that of female (191.30/100 000). The incidence rate of age 0-45 group was low, but it increased dramatically after age of 45. The incidence rate rose with age and especially for 75 age groups, with 2.75% APC, which has statistical significance(t=4.65, P < 0.001). Conclusion In 2008 to 2018, the incidence of stroke in Shenzhen was relatively stuble, but the incidence of the high age group showed a significant increase, so it is necessary to pay more attention to the elderly. -
Key words:
- Stroke /
- Incidence /
- Trend analysis
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表 1 2008―2018年深圳市脑卒中发病情况(/10万)
Table 1. The incidence of stroke in Shenzhen from 2008 to 2018 (/100 000)
年份 总体 男性 女性 新发病例数(例) 粗率 中标率 世标率 缺血性脑卒中发病率 出血性脑卒中发病率 新发病例数(例) 粗率 中标率 世标率 缺血性脑卒中发病率 出血性脑卒中发病率 新发病例数(例) 粗率 中标率 世标率 缺血性脑卒中发病率 出血性脑卒中发病率 2008 4 653 211.28 402.15 354.28 172.23 38.55 2 649 226.22 457.94 403.20 180.79 44.83 2 004 194.33 348.24 307.79 162.52 31.42 2009 5 062 215.62 411.62 362.80 190.58 38.87 2 823 226.20 454.09 399.05 185.02 40.79 2 239 203.62 368.60 326.58 171.70 31.56 2010 4 810 195.34 372.51 327.80 16.33 68.00 2 740 209.49 423.38 372.32 172.79 36.47 2 070 179.31 322.70 284.81 152.45 26.68 2011 4 916 189.47 336.41 296.20 159.64 29.52 2 830 205.95 390.15 342.38 90.80 33.99 2 086 170.91 283.95 251.48 68.83 24.50 2012 5 972 215.00 385.87 340.16 182.24 32.33 3 372 230.36 444.20 391.36 230.36 39.69 2 600 197.90 332.36 293.83 173.31 24.13 2013 6 507 217.59 392.22 347.16 184.82 32.14 3 755 239.87 467.98 414.03 200.14 38.78 2 752 193.12 324.23 288.08 168.00 24.84 2014 7 027 218.68 392.55 348.36 186.69 31.31 4 069 243.59 473.30 419.47 203.41 39.03 2 958 191.71 319.72 285.01 168.58 22.94 2015 7 377 214.70 387.43 344.57 186.96 27.01 4 219 236.48 462.12 411.26 236.48 33.91 3 158 191.17 321.49 286.66 170.77 19.55 2016 8 290 224.20 421.34 373.79 190.8 32.05 4 760 251.94 479.36 423.27 209.43 40.81 3 530 195.22 362.95 324.45 171.33 22.90 2017 9 307 227.21 427.24 379.29 196.21 30.27 5 330 256.90 485.61 429.91 218.34 37.74 3 977 196.74 368.25 328.66 173.49 22.61 2018 9 915 222.95 421.60 373.89 189.58 31.66 5 759 257.70 486.03 318.07 214.83 40.72 4 156 187.86 356.74 318.07 164.08 22.51 合计 73 836 215.48 397.77 352.11 182.95 31.76 42 306 237.89 460.29 406.78 198.21 38.73 31 530 191.30 337.82 300.39 166.48 24.24 APC(%) 1.12 0.84 0.96 8.76 -4.72 1.87 1.21 1.31 3.96 -0.92 0.28 0.43 0.57 2.33 -4.11 t值 2.07 1.13 1.28 0.99 -1.92 3.46 1.87 1.99 1.34 -0.97 0.47 0.46 0.60 0.71 -4.70 P值 0.07 0.29 0.24 0.35 0.09 0.01 0.10 0.08 0.22 0.36 0.65 0.66 0.57 0.50 0.00 表 2 2008―2018年深圳市脑卒中年龄别发病率变化趋势(/10万)
Table 2. The trend of stroke incidence by age in Shenzhen from 2008 to 2018 (/100 000)
年份 年龄组(岁) <30 30~<45 45~<60 60~<75 ≥75 2008 6.62 45.13 316.43 1 759.69 4 115.04 2009 6.78 46.06 302.21 1 745.45 4 556.79 2010 5.92 38.00 287.08 1 487.87 4 369.39 2011 3.34 33.78 272.13 1 344.45 3 863.21 2012 4.28 37.52 281.27 1 603.62 4 445.92 2013 4.89 33.37 286.96 1 533.65 4 831.97 2014 6.64 34.67 290.42 1 456.77 5 020.95 2015 5.05 33.31 278.85 1 431.75 5 044.56 2016 6.21 30.57 294.76 1 593.78 5 291.03 2017 5.97 34.30 321.26 1 588.62 5 352.20 2018 6.31 32.95 321.04 1 643.82 5 136.09 APC (%) 0.60 -3.14 0.43 -0.44 2.75 t值 0.27 -4.15 0.77 -0.54 4.65 P值 0.79 <0.01 0.46 0.61 <0.01 -
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