安徽省阜阳市HIV/HCV共感染者抗病毒治疗服药依从性及影响因素分析

范引光; 朱志伟; 马炜祥; 丁志强; 程国金; 戴色莺; 叶冬青

doi:10.16462/j.cnki.zhjbkz.2017.12.005

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名

邮箱

手机号码

标题

留言内容

验证码

安徽省阜阳市HIV/HCV共感染者抗病毒治疗服药依从性及影响因素分析

doi: 10.16462/j.cnki.zhjbkz.2017.12.005

1. 安徽医科大学公共卫生学院流行病与卫生统计学系, 安徽合肥 230032;
2. 阜阳市京九区卫生站, 安徽阜阳 236000;
3. 安徽省疾病预防控制中心艾滋病防治科, 安徽合肥 230000

基金项目:

安徽省自然科学基金（1608085MH174）；省级质量工程研究项目（2016jxxm0522）；国家级大学生创新创业项目（201710366028）

详细信息

作者简介:
范引光(1980-),男,安徽蒙城人,副教授,博士。主要研究方向:传染病流行病学。

中图分类号: R181
计量
- 文章访问数: 369
- HTML全文浏览量: 47
- PDF下载量: 38
- 被引次数: 0
出版历程
- 收稿日期: 2017-06-20
- 修回日期: 2017-09-10

Study on influencial factors of adherence to anti-retroviral treatment among people who co-infected with HIV/HCV in Fuyang City, Anhui Province

1. Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei 230032, China;
2. Health Station of Jingjiu District, Fuyang City, Fuyang 236000, China;
3. AIDS Department of Anhui Provincial Center for Disease Control and Provention, Hefei 230000, China

摘要

摘要: 目的探讨安徽省人类免疫缺陷病毒（human immunodeficiency virus，HIV）/丙型肝炎病毒（hepatitis C virus，HCV）共感染者抗病毒治疗服药依从性现状及其影响因素，为制定综合管理策略提供理论依据。方法采用横断面研究方法，对安徽省阜阳市接受抗病毒治疗1年以上的HIV/HCV共感染者进行问卷调查，收集患者的一般信息和服药情况，采用多因素Logistic回归分析对其服药依从性的影响因素进行分析。结果 256例HIV/HCV共感染者在过去1个月内抗病毒治疗的服药不依从率为34.0%，结婚年限较长（OR=3.049，95%CI：1.435~6.481，P=0.004）、抗病毒治疗时间较长（OR=1.803，95%CI：1.251~2.599，P=0.002）和饮酒者（OR=2.512，95%CI：1.152~5.478，P=0.021）抗病毒治疗依从性较差，而女性（OR=0.180，95%CI：0.089~0.366，P<0.001）和设置服药提醒者（OR=0.315，95%CI：0.159~0.626，P=0.001）的抗病毒治疗依从性较好。结论降低社会公众的艾滋病歧视和提高HIV/HCV共感染者抗病毒治疗的信心，是改善抗病毒治疗服药依从性的关键。
- HIV /
- 获得性免疫缺陷综合征 /
- 肝炎病毒 /
- 抗病毒药
Abstract: Objective To investigate the adherence to anti-retroviral treatment and related factors among human immunodeficiency virus (HIV) and hepatitis C virus (HCV) co-infectors. Methods In this cross-sectional study, 256 HIV and HCV co-infectors were recruited by convenience sampling method, and information about demography, taking medicine and therapy were collected and analyzed. Results A total of 256 HIV/HCV co-infectors were investigated, 34.0% of them missed dose in the last month. Multiple Logistic regression analysis showed that HIV/HCV co-infectors with long marriage (OR=3.049, 95% CI:1.435-6.481, P=0.004), longer time of treatment with antiretroviral therapy (ART) (OR=1.803, 95% CI:1.251-2.599, P=0.002), frequent alcohol consumption (OR=2.512, 95% CI:1.152-5.478, P=0.021) were risk factors of missed dose, while female (OR=0.180, 95% CI:0.089-0.366, P<0.001) and co-infectors who take a reminder method (OR=0.315, 95% CI:0.159-0.626, P=0.001) were protective factors for missed dose. Conclusions The ART adherence rate of HIV/HCV co-infectors was lower in Anhui Province, comprehensive intervention measures should be taken to promote the ART adherence.
- HIV /
- Acquired immunodeficiency syndrome /
- Hepatitis viruses /
- Antiviral agents