Abstract: Objective To study the length of patient delay and health system delay, and influence on the treatment outcomes, analyze the influencing factors of delays among adolescents with new smear positive tuberculosis(TB) in Guangxi Zhuang Autonomous Region of China.Methods New smear-positive pulmonary tuberculosis patients aged 10-19 years managed by Guangxi Zhuang Autonomous Region during the period from 2010 to 2015 were collected. Descriptive study was used to analyze the patients' demographic, clinical characteristics, different delay level and treatment outcome. Descriptive statistics and multivariate Logistic regression analysis were employed.Results A total of 2 196 adolescents were retrieved in the study. The median patient delay was 36 days and health system delay was 1 days, respectively. 2 122 cases were cured, the cure rate was 96.6%. Male, students adolescents were more likely to have shorter patient delay. Had cavitation on chest (OR=1.31, 95% CI:1.10-1.57, P=0.002) were more likely to have long patient delay. Ethnic minorities, migrants, referral to the TB hospital and cavitation on chest were more likely to have long health system delay. Predictors for cure included intensive treatment supervision and drug adherence for six months.Conclusions The delay periods of adolescents TB were lower than that of the general population, the cure rate was higher than the national planning indicators requirements. Occupation and pulmonary cavity were associated with patient delays, ethnic, patients with source and pulmonary cavity were associated with health system delay.