摘要:
目的 探讨华东沿海地区成年女性人工流产与糖尿病之间的关系。方法 研究对象来自于2017年2~8月在山东省荣成地区进行的流行病学调查，通过问卷调查和体格检查等方式收集受试者的相关信息。采用多元Logistic回归分析来估计人工流产与糖尿病的关联。结果 44 806名成年女性受试者纳入最终分析，其中无人工流产、1次人工流产、2次人工流产、3次人工流产、4次及以上次数人工流产人群对应的糖尿病患病率分别为16.3%、17.2%、18.3%、18.8%和20.2%。与无人工流产的人群比较，2次人工流产（OR=1.11，95%CI：1.02~1.21，P=0.021），3次人工流产（OR=1.17，95%CI：1.02~1.34，P=0.027）和4次及以上次数人工流产（OR=1.24，95%CI：1.03~1.50，P=0.026）人群患糖尿病风险增加。结论 华东沿海地区成年女性人群人工流产与糖尿病之间存在关联，且人工流产次数越多糖尿病患病率越高。
Abstract:
Objective To test the association between induced abortion and diabetes among female adults in coastal areas of East China. Methods An epidemiological investigation was conducted among female adults in Rongcheng of Shandong Province, from February 2017 to August 2017. Standardized questionnaire and anthropometric measurements were conducted to collect each participant's relevant information. Multivariable Logistic regression models were performed to determine the association between induced abortion and diabetes. Results A total of 44 806 female adults were enrolled in the final analysis. The prevalence of diabetes in those without induced abortion, with once, twice, three times, four and more than four times induced abortion was 16.3%, 17.2%, 18.3%, 18.8% and 20.2%, respectively. Overall, compared with participants without induced abortion, the significantly higher prevalence of diabetes was observed in those with twice induced abortion (OR=1.11, 95% CI:1.02-1.21, P=0.021), three times induced abortion (OR=1.17, 95% CI:1.02-1.34, P=0.027), four and more than four times induced abortion (OR=1.24, 95% CI:1.03-1.50, P=0.026). Conclusion The induced abortion is significantly associated with the prevalence of diabetes in female adults in coastal areas of Eastern China, and the more times of induced abortion, the higher prevalence of diabetes is.
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